Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3353c

Experiment: Palmitic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3351c and Rv3352c are separated by 81 nucleotidesRv3352c and Rv3353c are separated by 142 nucleotidesRv3353c and Rv3354 are separated by 114 nucleotidesRv3354 and Rv3355c are separated by 13 nucleotidesRv3355c and Rv3356c overlap by 4 nucleotides Rv3351c: Rv3351c - Conserved hypothetical protein, at 3,767,346 to 3,768,140 Rv3351c Rv3352c: Rv3352c - Possible oxidoreductase, at 3,768,222 to 3,768,593 Rv3352c Rv3353c: Rv3353c - Conserved hypothetical protein, at 3,768,736 to 3,768,996 Rv3353c Rv3354: Rv3354 - Conserved hypothetical protein, at 3,769,111 to 3,769,500 Rv3354 Rv3355c: Rv3355c - Probable integral membrane protein, at 3,769,514 to 3,769,807 Rv3355c Rv3356c: Rv3356c - Probable bifunctional protein FolD: methylenetetrahydrofolate dehydrogenase + methenyltetrahydrofolate cyclohydrolase, at 3,769,804 to 3,770,649 Rv3356c Position (kb) 3768 3769Strain fitness (log2 ratio) -2 -1 0 1 2at 3767.786 kb on - strand, within Rv3351cat 3767.786 kb on - strand, within Rv3351cat 3767.995 kb on + strand, within Rv3351cat 3767.995 kb on + strand, within Rv3351cat 3768.002 kb on + strand, within Rv3351cat 3768.003 kb on - strand, within Rv3351cat 3768.020 kb on - strand, within Rv3351cat 3768.035 kb on + strand, within Rv3351cat 3768.036 kb on - strand, within Rv3351cat 3768.596 kb on + strandat 3768.596 kb on + strandat 3768.596 kb on + strandat 3768.597 kb on - strandat 3768.597 kb on - strandat 3768.597 kb on - strandat 3768.597 kb on - strandat 3768.597 kb on - strandat 3768.687 kb on + strandat 3768.687 kb on + strandat 3768.687 kb on + strandat 3768.687 kb on + strandat 3768.687 kb on + strandat 3768.687 kb on + strandat 3768.688 kb on - strandat 3768.688 kb on - strandat 3768.688 kb on - strandat 3768.806 kb on + strand, within Rv3353cat 3768.929 kb on - strand, within Rv3353cat 3768.929 kb on - strand, within Rv3353cat 3769.017 kb on - strandat 3769.063 kb on + strandat 3769.064 kb on - strandat 3769.064 kb on - strandat 3769.065 kb on + strandat 3769.065 kb on + strandat 3769.066 kb on - strandat 3769.066 kb on - strandat 3769.066 kb on - strandat 3769.066 kb on - strandat 3769.066 kb on - strandat 3769.258 kb on + strand, within Rv3354at 3769.259 kb on - strand, within Rv3354at 3769.420 kb on + strand, within Rv3354at 3769.421 kb on - strand, within Rv3354at 3769.421 kb on - strand, within Rv3354at 3769.516 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Palmitic 100 uM (C)
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3,767,786 - Rv3351c 0.55 -0.6
3,767,786 - Rv3351c 0.55 +0.7
3,767,995 + Rv3351c 0.82 -0.1
3,767,995 + Rv3351c 0.82 -0.1
3,768,002 + Rv3351c 0.83 -0.2
3,768,003 - Rv3351c 0.83 -1.4
3,768,020 - Rv3351c 0.85 +1.8
3,768,035 + Rv3351c 0.87 -0.7
3,768,036 - Rv3351c 0.87 -0.0
3,768,596 + -0.2
3,768,596 + -0.6
3,768,596 + +0.2
3,768,597 - -1.3
3,768,597 - -0.1
3,768,597 - -0.0
3,768,597 - +0.3
3,768,597 - -0.9
3,768,687 + +0.5
3,768,687 + -0.5
3,768,687 + +0.1
3,768,687 + -0.4
3,768,687 + -0.4
3,768,687 + -0.1
3,768,688 - -0.7
3,768,688 - +0.1
3,768,688 - -0.7
3,768,806 + Rv3353c 0.27 -2.6
3,768,929 - Rv3353c 0.74 -0.4
3,768,929 - Rv3353c 0.74 -0.6
3,769,017 - +0.7
3,769,063 + +0.1
3,769,064 - -0.2
3,769,064 - -0.4
3,769,065 + -0.1
3,769,065 + +0.2
3,769,066 - +0.1
3,769,066 - -0.5
3,769,066 - -0.3
3,769,066 - -0.3
3,769,066 - -0.5
3,769,258 + Rv3354 0.38 +0.4
3,769,259 - Rv3354 0.38 -0.1
3,769,420 + Rv3354 0.79 -1.2
3,769,421 - Rv3354 0.79 -0.2
3,769,421 - Rv3354 0.79 -0.0
3,769,516 - -0.2

Or see this region's nucleotide sequence