Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1190

Experiment: Palmitic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1188 and Rv1189 are separated by 81 nucleotidesRv1189 and Rv1190 are separated by 15 nucleotidesRv1190 and Rv1191 are separated by 72 nucleotides Rv1188: Rv1188 - Probable proline dehydrogenase, at 1,331,021 to 1,332,010 Rv1188 Rv1189: Rv1189 - Possible alternative RNA polymerase sigma factor SigI, at 1,332,092 to 1,332,964 Rv1189 Rv1190: Rv1190 - Conserved hypothetical protein, at 1,332,980 to 1,333,858 Rv1190 Rv1191: Rv1191 - Conserved protein, at 1,333,931 to 1,334,845 Rv1191 Position (kb) 1332 1333 1334Strain fitness (log2 ratio) -1 0 1at 1332.913 kb on - strandat 1332.913 kb on - strandat 1333.297 kb on - strand, within Rv1190at 1333.605 kb on - strand, within Rv1190at 1333.605 kb on - strand, within Rv1190at 1333.637 kb on + strand, within Rv1190at 1333.637 kb on + strand, within Rv1190at 1333.638 kb on - strand, within Rv1190at 1333.924 kb on - strandat 1334.093 kb on + strand, within Rv1191at 1334.110 kb on + strand, within Rv1191at 1334.264 kb on + strand, within Rv1191at 1334.264 kb on + strand, within Rv1191at 1334.264 kb on + strand, within Rv1191at 1334.264 kb on + strand, within Rv1191at 1334.265 kb on - strand, within Rv1191at 1334.265 kb on - strand, within Rv1191at 1334.265 kb on - strand, within Rv1191at 1334.486 kb on + strand, within Rv1191

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Per-strain Table

Position Strand Gene LocusTag Fraction Palmitic 100 uM (C)
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1,332,913 - -0.8
1,332,913 - -0.1
1,333,297 - Rv1190 0.36 -0.4
1,333,605 - Rv1190 0.71 -1.2
1,333,605 - Rv1190 0.71 -0.5
1,333,637 + Rv1190 0.75 -1.0
1,333,637 + Rv1190 0.75 -0.6
1,333,638 - Rv1190 0.75 +0.3
1,333,924 - -0.1
1,334,093 + Rv1191 0.18 +0.8
1,334,110 + Rv1191 0.20 -0.5
1,334,264 + Rv1191 0.36 -0.7
1,334,264 + Rv1191 0.36 +0.6
1,334,264 + Rv1191 0.36 +0.1
1,334,264 + Rv1191 0.36 -0.1
1,334,265 - Rv1191 0.37 -0.4
1,334,265 - Rv1191 0.37 -1.7
1,334,265 - Rv1191 0.37 -1.4
1,334,486 + Rv1191 0.61 -0.4

Or see this region's nucleotide sequence