Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3642c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3640c and Rv3641c are separated by 175 nucleotidesRv3641c and Rv3642c are separated by 10 nucleotidesRv3642c and Rv3643 are separated by 394 nucleotidesRv3643 and GFF3786 are separated by 13 nucleotidesGFF3786 and Rv3644c are separated by 78 nucleotides Rv3640c: Rv3640c - Probable transposase, at 4,078,520 to 4,079,749 Rv3640c Rv3641c: Rv3641c - Possible cell filamentation protein Fic, at 4,079,925 to 4,080,560 Rv3641c Rv3642c: Rv3642c - Hypothetical protein, at 4,080,571 to 4,080,765 Rv3642c Rv3643: Rv3643 - Hypothetical protein, at 4,081,160 to 4,081,351 Rv3643 GFF3786 - tRNA-Thr, at 4,081,365 to 4,081,437 GFF3786 Rv3644c: Rv3644c - Possible DNA polymerase, at 4,081,516 to 4,082,721 Rv3644c Position (kb) 4080 4081Strain fitness (log2 ratio) -1 0 1 2at 4079.812 kb on - strandat 4079.867 kb on + strandat 4079.917 kb on + strandat 4079.917 kb on + strandat 4079.917 kb on + strandat 4079.935 kb on + strandat 4080.136 kb on + strand, within Rv3641cat 4080.137 kb on - strand, within Rv3641cat 4080.137 kb on - strand, within Rv3641cat 4080.361 kb on + strand, within Rv3641cat 4080.511 kb on + strandat 4080.512 kb on - strandat 4080.512 kb on - strandat 4080.584 kb on + strandat 4080.584 kb on + strandat 4080.585 kb on - strandat 4080.638 kb on + strand, within Rv3642cat 4080.638 kb on + strand, within Rv3642cat 4080.861 kb on + strandat 4080.888 kb on + strandat 4080.960 kb on + strandat 4080.961 kb on - strandat 4080.961 kb on - strandat 4081.174 kb on - strandat 4081.236 kb on - strand, within Rv3643at 4081.286 kb on + strand, within Rv3643at 4081.287 kb on - strand, within Rv3643at 4081.339 kb on + strandat 4081.340 kb on - strandat 4081.342 kb on - strandat 4081.342 kb on - strandat 4081.476 kb on + strandat 4081.476 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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4,079,812 - -0.8
4,079,867 + +1.0
4,079,917 + +0.5
4,079,917 + +1.6
4,079,917 + -0.5
4,079,935 + -0.0
4,080,136 + Rv3641c 0.33 +0.0
4,080,137 - Rv3641c 0.33 -0.5
4,080,137 - Rv3641c 0.33 +0.2
4,080,361 + Rv3641c 0.69 -0.1
4,080,511 + -1.1
4,080,512 - +0.7
4,080,512 - +0.3
4,080,584 + -0.8
4,080,584 + +2.7
4,080,585 - +0.0
4,080,638 + Rv3642c 0.34 +0.5
4,080,638 + Rv3642c 0.34 +0.6
4,080,861 + +0.1
4,080,888 + +0.4
4,080,960 + +0.2
4,080,961 - +0.1
4,080,961 - -0.1
4,081,174 - -0.1
4,081,236 - Rv3643 0.40 -0.5
4,081,286 + Rv3643 0.66 -0.7
4,081,287 - Rv3643 0.66 -1.1
4,081,339 + -0.6
4,081,340 - +2.5
4,081,342 - -0.7
4,081,342 - +0.1
4,081,476 + +0.8
4,081,476 + +0.0

Or see this region's nucleotide sequence