Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3394c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3393 and Rv3394c are separated by 54 nucleotidesRv3394c and Rv3395c overlap by 4 nucleotidesRv3395c and Rv3395A are separated by 82 nucleotides Rv3393: Rv3393 - Probable nucleoside hydrolase IunH (purine nucleosidase), at 3,808,461 to 3,809,387 Rv3393 Rv3394c: Rv3394c - Conserved hypothetical protein, at 3,809,442 to 3,811,025 Rv3394c Rv3395c: Rv3395c - Conserved hypothetical protein, at 3,811,022 to 3,811,636 Rv3395c Rv3395A: Rv3395A - Probable membrane protein, at 3,811,719 to 3,812,345 Rv3395A Position (kb) 3809 3810 3811 3812Strain fitness (log2 ratio) -2 -1 0 1at 3808.449 kb on - strandat 3808.471 kb on + strandat 3808.518 kb on + strandat 3808.717 kb on + strand, within Rv3393at 3809.134 kb on - strand, within Rv3393at 3809.167 kb on - strand, within Rv3393at 3809.175 kb on + strand, within Rv3393at 3809.176 kb on - strand, within Rv3393at 3809.177 kb on + strand, within Rv3393at 3809.178 kb on - strand, within Rv3393at 3809.465 kb on - strandat 3809.805 kb on + strand, within Rv3394cat 3810.818 kb on + strand, within Rv3394cat 3810.818 kb on + strand, within Rv3394cat 3810.989 kb on + strandat 3810.990 kb on - strandat 3811.113 kb on + strand, within Rv3395cat 3811.730 kb on + strandat 3811.730 kb on + strandat 3811.730 kb on + strandat 3811.777 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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3,808,449 - +0.2
3,808,471 + -0.0
3,808,518 + +0.0
3,808,717 + Rv3393 0.28 +0.0
3,809,134 - Rv3393 0.73 -0.3
3,809,167 - Rv3393 0.76 -0.2
3,809,175 + Rv3393 0.77 -0.6
3,809,176 - Rv3393 0.77 -0.2
3,809,177 + Rv3393 0.77 -1.3
3,809,178 - Rv3393 0.77 -0.2
3,809,465 - -0.3
3,809,805 + Rv3394c 0.23 -1.3
3,810,818 + Rv3394c 0.87 -0.3
3,810,818 + Rv3394c 0.87 -1.1
3,810,989 + -0.3
3,810,990 - -1.3
3,811,113 + Rv3395c 0.15 -0.4
3,811,730 + -1.8
3,811,730 + -1.0
3,811,730 + +0.2
3,811,777 + -0.4

Or see this region's nucleotide sequence