Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3306c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3305c and Rv3306c overlap by 4 nucleotidesRv3306c and Rv3307 are separated by 64 nucleotidesRv3307 and Rv3308 are separated by 3 nucleotides Rv3305c: Rv3305c - Possible N-acyl-L-amino acid amidohydrolase AmiA1 (N-acyl-L-amino acid aminohydrolase), at 3,691,639 to 3,692,808 Rv3305c Rv3306c: Rv3306c - Probable amidohydrolase AmiB1 (aminohydrolase), at 3,692,805 to 3,693,989 Rv3306c Rv3307: Rv3307 - Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP), at 3,694,054 to 3,694,860 Rv3307 Rv3308: Rv3308 - Probable phosphomannomutase PmmB (phosphomannose mutase), at 3,694,864 to 3,696,468 Rv3308 Position (kb) 3692 3693 3694Strain fitness (log2 ratio) -2 -1 0 1at 3691.860 kb on + strand, within Rv3305cat 3691.963 kb on + strand, within Rv3305cat 3692.694 kb on + strandat 3692.703 kb on - strandat 3692.727 kb on - strandat 3693.278 kb on - strand, within Rv3306cat 3693.375 kb on + strand, within Rv3306cat 3693.419 kb on + strand, within Rv3306cat 3693.998 kb on + strandat 3694.040 kb on + strandat 3694.268 kb on + strand, within Rv3307at 3694.349 kb on - strand, within Rv3307at 3694.396 kb on - strand, within Rv3307at 3694.396 kb on - strand, within Rv3307at 3694.396 kb on - strand, within Rv3307at 3694.532 kb on - strand, within Rv3307at 3694.615 kb on + strand, within Rv3307at 3694.615 kb on + strand, within Rv3307at 3694.730 kb on + strand, within Rv3307at 3694.858 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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3,691,860 + Rv3305c 0.19 -0.6
3,691,963 + Rv3305c 0.28 -0.8
3,692,694 + +0.9
3,692,703 - -0.3
3,692,727 - -0.4
3,693,278 - Rv3306c 0.40 -0.8
3,693,375 + Rv3306c 0.48 -2.3
3,693,419 + Rv3306c 0.52 +0.9
3,693,998 + -0.4
3,694,040 + -0.3
3,694,268 + Rv3307 0.27 -0.5
3,694,349 - Rv3307 0.37 -0.5
3,694,396 - Rv3307 0.42 -0.5
3,694,396 - Rv3307 0.42 +0.1
3,694,396 - Rv3307 0.42 -0.4
3,694,532 - Rv3307 0.59 -0.7
3,694,615 + Rv3307 0.70 -0.5
3,694,615 + Rv3307 0.70 -0.7
3,694,730 + Rv3307 0.84 -0.5
3,694,858 + +0.4

Or see this region's nucleotide sequence