Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2982c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2981c and Rv2982c are separated by 77 nucleotidesRv2982c and Rv2983 are separated by 118 nucleotidesRv2983 and Rv2984 are separated by 91 nucleotides Rv2981c: Rv2981c - Probable D-alanine--D-alanine ligase DdlA (D-alanylalanine synthetase) (D-ala-D-ala ligase), at 3,336,796 to 3,337,917 Rv2981c Rv2982c: Rv2982c - Probable glycerol-3-phosphate dehydrogenase [NAD(P)+] GpdA2 (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase), at 3,337,995 to 3,338,999 Rv2982c Rv2983: Rv2983 - Conserved hypothetical alanine rich protein, at 3,339,118 to 3,339,762 Rv2983 Rv2984: Rv2984 - Polyphosphate kinase PPK (polyphosphoric acid kinase) (ATP-polyphosphate phosphotransferase), at 3,339,854 to 3,342,082 Rv2984 Position (kb) 3337 3338 3339Strain fitness (log2 ratio) -1 0 1 2at 3337.909 kb on - strandat 3338.057 kb on + strandat 3338.058 kb on - strandat 3338.104 kb on + strand, within Rv2982cat 3338.104 kb on + strand, within Rv2982cat 3338.461 kb on + strand, within Rv2982cat 3338.473 kb on + strand, within Rv2982cat 3338.823 kb on + strand, within Rv2982cat 3338.855 kb on - strand, within Rv2982cat 3338.865 kb on - strand, within Rv2982cat 3338.865 kb on - strand, within Rv2982cat 3338.988 kb on + strandat 3339.010 kb on + strandat 3339.725 kb on + strandat 3339.996 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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3,337,909 - -0.6
3,338,057 + -1.0
3,338,058 - +0.7
3,338,104 + Rv2982c 0.11 -1.0
3,338,104 + Rv2982c 0.11 +1.9
3,338,461 + Rv2982c 0.46 -1.6
3,338,473 + Rv2982c 0.48 -1.3
3,338,823 + Rv2982c 0.82 -1.4
3,338,855 - Rv2982c 0.86 -0.6
3,338,865 - Rv2982c 0.87 -1.0
3,338,865 - Rv2982c 0.87 -1.2
3,338,988 + -0.9
3,339,010 + -0.2
3,339,725 + -0.4
3,339,996 + -0.5

Or see this region's nucleotide sequence