Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2888c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2886c and Rv2887 overlap by 2 nucleotidesRv2887 and Rv2888c are separated by 13 nucleotidesRv2888c and Rv2889c are separated by 6 nucleotidesRv2889c and Rv2890c are separated by 11 nucleotides Rv2886c: Rv2886c - Probable resolvase, at 3,195,545 to 3,196,432 Rv2886c Rv2887: Rv2887 - Probable transcriptional regulatory protein, at 3,196,431 to 3,196,850 Rv2887 Rv2888c: Rv2888c - Probable amidase AmiC (aminohydrolase), at 3,196,864 to 3,198,285 Rv2888c Rv2889c: Rv2889c - Probable elongation factor Tsf (EF-ts), at 3,198,292 to 3,199,107 Rv2889c Rv2890c: Rv2890c - 30S ribosomal protein S2 RpsB, at 3,199,119 to 3,199,982 Rv2890c Position (kb) 3196 3197 3198 3199Strain fitness (log2 ratio) -1 0 1at 3195.918 kb on - strand, within Rv2886cat 3196.080 kb on + strand, within Rv2886cat 3196.081 kb on - strand, within Rv2886cat 3196.133 kb on - strand, within Rv2886cat 3196.144 kb on + strand, within Rv2886cat 3196.311 kb on + strand, within Rv2886cat 3196.312 kb on - strand, within Rv2886cat 3196.438 kb on + strandat 3196.487 kb on - strand, within Rv2887at 3196.709 kb on + strand, within Rv2887at 3196.849 kb on - strandat 3196.922 kb on + strandat 3196.923 kb on - strandat 3196.923 kb on - strandat 3196.923 kb on - strandat 3196.923 kb on - strandat 3197.011 kb on + strand, within Rv2888cat 3197.100 kb on + strand, within Rv2888cat 3197.111 kb on + strand, within Rv2888cat 3197.111 kb on + strand, within Rv2888cat 3197.194 kb on + strand, within Rv2888cat 3197.194 kb on + strand, within Rv2888cat 3197.286 kb on + strand, within Rv2888cat 3197.286 kb on + strand, within Rv2888cat 3197.354 kb on + strand, within Rv2888cat 3197.354 kb on + strand, within Rv2888cat 3197.355 kb on - strand, within Rv2888cat 3197.355 kb on - strand, within Rv2888cat 3197.410 kb on + strand, within Rv2888cat 3197.422 kb on + strand, within Rv2888cat 3197.422 kb on + strand, within Rv2888cat 3197.423 kb on - strand, within Rv2888cat 3197.423 kb on - strand, within Rv2888cat 3197.501 kb on - strand, within Rv2888cat 3197.503 kb on + strand, within Rv2888cat 3197.503 kb on + strand, within Rv2888cat 3197.503 kb on + strand, within Rv2888cat 3197.503 kb on + strand, within Rv2888cat 3197.569 kb on - strand, within Rv2888cat 3197.594 kb on + strand, within Rv2888cat 3197.667 kb on - strand, within Rv2888cat 3197.831 kb on + strand, within Rv2888cat 3197.831 kb on + strand, within Rv2888cat 3197.838 kb on + strand, within Rv2888cat 3197.850 kb on + strand, within Rv2888cat 3197.956 kb on + strand, within Rv2888cat 3197.981 kb on + strand, within Rv2888cat 3198.125 kb on + strand, within Rv2888cat 3198.125 kb on + strand, within Rv2888cat 3198.126 kb on - strand, within Rv2888cat 3198.293 kb on + strandat 3199.121 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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3,195,918 - Rv2886c 0.42 -0.3
3,196,080 + Rv2886c 0.60 -0.4
3,196,081 - Rv2886c 0.60 -0.8
3,196,133 - Rv2886c 0.66 +0.0
3,196,144 + Rv2886c 0.67 -0.0
3,196,311 + Rv2886c 0.86 -0.5
3,196,312 - Rv2886c 0.86 -0.2
3,196,438 + +0.9
3,196,487 - Rv2887 0.13 +1.4
3,196,709 + Rv2887 0.66 -0.4
3,196,849 - -1.1
3,196,922 + +0.9
3,196,923 - -0.1
3,196,923 - +0.4
3,196,923 - -0.5
3,196,923 - -0.5
3,197,011 + Rv2888c 0.10 -1.0
3,197,100 + Rv2888c 0.17 -0.5
3,197,111 + Rv2888c 0.17 +0.1
3,197,111 + Rv2888c 0.17 -1.3
3,197,194 + Rv2888c 0.23 -0.3
3,197,194 + Rv2888c 0.23 -0.4
3,197,286 + Rv2888c 0.30 -0.5
3,197,286 + Rv2888c 0.30 +0.5
3,197,354 + Rv2888c 0.34 -0.4
3,197,354 + Rv2888c 0.34 +1.1
3,197,355 - Rv2888c 0.35 -0.4
3,197,355 - Rv2888c 0.35 +0.0
3,197,410 + Rv2888c 0.38 -0.5
3,197,422 + Rv2888c 0.39 -1.6
3,197,422 + Rv2888c 0.39 +0.4
3,197,423 - Rv2888c 0.39 +0.4
3,197,423 - Rv2888c 0.39 +0.2
3,197,501 - Rv2888c 0.45 -0.7
3,197,503 + Rv2888c 0.45 -0.5
3,197,503 + Rv2888c 0.45 -0.4
3,197,503 + Rv2888c 0.45 -0.4
3,197,503 + Rv2888c 0.45 +0.2
3,197,569 - Rv2888c 0.50 -0.9
3,197,594 + Rv2888c 0.51 -0.6
3,197,667 - Rv2888c 0.56 -0.9
3,197,831 + Rv2888c 0.68 -0.3
3,197,831 + Rv2888c 0.68 -0.4
3,197,838 + Rv2888c 0.68 -0.4
3,197,850 + Rv2888c 0.69 -0.4
3,197,956 + Rv2888c 0.77 -0.3
3,197,981 + Rv2888c 0.79 -0.1
3,198,125 + Rv2888c 0.89 +0.3
3,198,125 + Rv2888c 0.89 -0.4
3,198,126 - Rv2888c 0.89 +0.0
3,198,293 + -0.3
3,199,121 - -0.9

Or see this region's nucleotide sequence