Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1836c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1835c and Rv1836c are separated by 15 nucleotidesRv1836c and Rv1837c are separated by 119 nucleotides Rv1835c: Rv1835c - Conserved hypothetical protein, at 2,080,701 to 2,082,587 Rv1835c Rv1836c: Rv1836c - Conserved protein, at 2,082,603 to 2,084,636 Rv1836c Rv1837c: Rv1837c - Malate synthase G GlcB, at 2,084,756 to 2,086,981 Rv1837c Position (kb) 2082 2083 2084 2085Strain fitness (log2 ratio) -2 -1 0 1 2at 2081.614 kb on + strand, within Rv1835cat 2081.615 kb on - strand, within Rv1835cat 2081.639 kb on - strand, within Rv1835cat 2081.639 kb on - strand, within Rv1835cat 2081.639 kb on - strand, within Rv1835cat 2081.680 kb on + strand, within Rv1835cat 2081.726 kb on + strand, within Rv1835cat 2081.726 kb on + strand, within Rv1835cat 2081.726 kb on + strand, within Rv1835cat 2081.765 kb on - strand, within Rv1835cat 2081.781 kb on + strand, within Rv1835cat 2081.781 kb on + strand, within Rv1835cat 2081.781 kb on + strand, within Rv1835cat 2081.828 kb on - strand, within Rv1835cat 2081.828 kb on - strand, within Rv1835cat 2081.969 kb on - strand, within Rv1835cat 2081.969 kb on - strand, within Rv1835cat 2082.031 kb on + strand, within Rv1835cat 2082.032 kb on - strand, within Rv1835cat 2082.096 kb on + strand, within Rv1835cat 2082.118 kb on + strand, within Rv1835cat 2082.311 kb on + strand, within Rv1835cat 2082.386 kb on - strand, within Rv1835cat 2082.388 kb on + strand, within Rv1835cat 2082.490 kb on + strandat 2082.490 kb on + strandat 2082.490 kb on + strandat 2082.491 kb on - strandat 2082.502 kb on + strandat 2082.502 kb on + strandat 2082.553 kb on + strandat 2082.937 kb on + strand, within Rv1836cat 2083.355 kb on - strand, within Rv1836cat 2083.907 kb on + strand, within Rv1836cat 2083.959 kb on - strand, within Rv1836cat 2084.118 kb on + strand, within Rv1836cat 2084.119 kb on - strand, within Rv1836cat 2084.316 kb on - strand, within Rv1836cat 2084.536 kb on + strandat 2084.548 kb on - strandat 2084.548 kb on - strandat 2084.548 kb on - strandat 2084.548 kb on - strandat 2084.548 kb on - strandat 2084.688 kb on + strandat 2084.688 kb on + strandat 2084.689 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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2,081,614 + Rv1835c 0.48 -0.8
2,081,615 - Rv1835c 0.48 -0.5
2,081,639 - Rv1835c 0.50 +1.0
2,081,639 - Rv1835c 0.50 -0.2
2,081,639 - Rv1835c 0.50 +1.8
2,081,680 + Rv1835c 0.52 +0.1
2,081,726 + Rv1835c 0.54 -0.2
2,081,726 + Rv1835c 0.54 -0.4
2,081,726 + Rv1835c 0.54 +0.1
2,081,765 - Rv1835c 0.56 -0.7
2,081,781 + Rv1835c 0.57 -0.2
2,081,781 + Rv1835c 0.57 -1.3
2,081,781 + Rv1835c 0.57 -0.2
2,081,828 - Rv1835c 0.60 -0.6
2,081,828 - Rv1835c 0.60 -0.7
2,081,969 - Rv1835c 0.67 +0.1
2,081,969 - Rv1835c 0.67 +1.7
2,082,031 + Rv1835c 0.70 -0.3
2,082,032 - Rv1835c 0.71 -0.2
2,082,096 + Rv1835c 0.74 -0.6
2,082,118 + Rv1835c 0.75 -0.8
2,082,311 + Rv1835c 0.85 -0.2
2,082,386 - Rv1835c 0.89 -0.6
2,082,388 + Rv1835c 0.89 -0.5
2,082,490 + -0.1
2,082,490 + +0.2
2,082,490 + -0.6
2,082,491 - +0.3
2,082,502 + -0.1
2,082,502 + -0.3
2,082,553 + +0.8
2,082,937 + Rv1836c 0.16 -1.1
2,083,355 - Rv1836c 0.37 -1.0
2,083,907 + Rv1836c 0.64 -1.0
2,083,959 - Rv1836c 0.67 -0.9
2,084,118 + Rv1836c 0.74 -0.2
2,084,119 - Rv1836c 0.75 -0.7
2,084,316 - Rv1836c 0.84 -1.1
2,084,536 + -0.3
2,084,548 - -0.7
2,084,548 - -0.7
2,084,548 - -0.2
2,084,548 - -0.6
2,084,548 - -2.3
2,084,688 + -0.6
2,084,688 + -1.5
2,084,689 - -0.2

Or see this region's nucleotide sequence