Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1639c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1638 and Rv1638A are separated by 56 nucleotidesRv1638A and Rv1639c are separated by 15 nucleotidesRv1639c and Rv1640c are separated by 58 nucleotides Rv1638: Rv1638 - Probable excinuclease ABC (subunit A-DNA-binding ATPase) UvrA, at 1,843,741 to 1,846,659 Rv1638 Rv1638A: Rv1638A - Conserved hypothetical protein, at 1,846,716 to 1,846,973 Rv1638A Rv1639c: Rv1639c - Conserved hypothetical membrane protein, at 1,846,989 to 1,848,458 Rv1639c Rv1640c: Rv1640c - Lysyl-tRNA synthetase 2 LysX, at 1,848,517 to 1,852,035 Rv1640c Position (kb) 1846 1847 1848 1849Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 1846.058 kb on - strand, within Rv1638at 1846.117 kb on + strand, within Rv1638at 1846.118 kb on - strand, within Rv1638at 1846.118 kb on - strand, within Rv1638at 1846.204 kb on + strand, within Rv1638at 1846.205 kb on - strand, within Rv1638at 1846.208 kb on + strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.237 kb on + strand, within Rv1638at 1846.340 kb on - strand, within Rv1638at 1846.382 kb on + strandat 1846.382 kb on + strandat 1846.382 kb on + strandat 1846.428 kb on + strandat 1846.449 kb on + strandat 1846.990 kb on + strandat 1847.324 kb on - strand, within Rv1639cat 1847.324 kb on - strand, within Rv1639cat 1847.462 kb on + strand, within Rv1639cat 1847.576 kb on - strand, within Rv1639cat 1847.674 kb on - strand, within Rv1639cat 1847.858 kb on - strand, within Rv1639cat 1848.038 kb on - strand, within Rv1639cat 1848.232 kb on + strand, within Rv1639cat 1848.233 kb on - strand, within Rv1639cat 1848.233 kb on - strand, within Rv1639cat 1848.396 kb on + strandat 1848.397 kb on - strandat 1848.397 kb on - strandat 1848.629 kb on + strandat 1848.629 kb on + strandat 1848.629 kb on + strandat 1848.630 kb on - strandat 1848.861 kb on - strandat 1848.861 kb on - strandat 1849.221 kb on - strand, within Rv1640cat 1849.231 kb on + strand, within Rv1640cat 1849.374 kb on - strand, within Rv1640c

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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1,846,058 - Rv1638 0.79 +0.6
1,846,117 + Rv1638 0.81 +0.4
1,846,118 - Rv1638 0.81 -0.2
1,846,118 - Rv1638 0.81 -3.2
1,846,204 + Rv1638 0.84 -0.5
1,846,205 - Rv1638 0.84 -1.1
1,846,208 + Rv1638 0.85 -2.3
1,846,209 - Rv1638 0.85 +0.3
1,846,209 - Rv1638 0.85 -1.1
1,846,209 - Rv1638 0.85 -0.4
1,846,209 - Rv1638 0.85 -0.1
1,846,209 - Rv1638 0.85 -0.4
1,846,237 + Rv1638 0.86 -1.6
1,846,340 - Rv1638 0.89 -0.9
1,846,382 + -1.3
1,846,382 + -0.7
1,846,382 + -0.7
1,846,428 + +0.1
1,846,449 + -1.5
1,846,990 + -1.0
1,847,324 - Rv1639c 0.23 -0.8
1,847,324 - Rv1639c 0.23 -0.4
1,847,462 + Rv1639c 0.32 -1.3
1,847,576 - Rv1639c 0.40 +0.9
1,847,674 - Rv1639c 0.47 -0.4
1,847,858 - Rv1639c 0.59 -0.6
1,848,038 - Rv1639c 0.71 +0.6
1,848,232 + Rv1639c 0.85 -0.2
1,848,233 - Rv1639c 0.85 -0.3
1,848,233 - Rv1639c 0.85 -0.5
1,848,396 + +0.2
1,848,397 - -0.4
1,848,397 - +0.1
1,848,629 + -0.8
1,848,629 + -1.0
1,848,629 + -1.7
1,848,630 - -1.0
1,848,861 - -0.2
1,848,861 - +2.9
1,849,221 - Rv1640c 0.20 -0.5
1,849,231 + Rv1640c 0.20 -0.5
1,849,374 - Rv1640c 0.24 +0.3

Or see this region's nucleotide sequence