Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1273c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1272c and Rv1273c overlap by 4 nucleotidesRv1273c and Rv1274 are separated by 146 nucleotidesRv1274 and Rv1275 overlap by 4 nucleotides Rv1272c: Rv1272c - Probable drugs-transport transmembrane ATP-binding protein ABC transporter, at 1,420,410 to 1,422,305 Rv1272c Rv1273c: Rv1273c - Probable drugs-transport transmembrane ATP-binding protein ABC transporter, at 1,422,302 to 1,424,050 Rv1273c Rv1274: Rv1274 - Possible lipoprotein LprB, at 1,424,197 to 1,424,754 Rv1274 Rv1275: Rv1275 - Possible lipoprotein LprC, at 1,424,751 to 1,425,293 Rv1275 Position (kb) 1422 1423 1424 1425Strain fitness (log2 ratio) -3 -2 -1 0 1at 1421.320 kb on - strand, within Rv1272cat 1421.320 kb on - strand, within Rv1272cat 1421.509 kb on + strand, within Rv1272cat 1422.358 kb on - strandat 1422.567 kb on + strand, within Rv1273cat 1422.567 kb on + strand, within Rv1273cat 1422.568 kb on - strand, within Rv1273cat 1422.568 kb on - strand, within Rv1273cat 1422.793 kb on - strand, within Rv1273cat 1423.020 kb on + strand, within Rv1273cat 1423.213 kb on - strand, within Rv1273cat 1423.822 kb on - strand, within Rv1273cat 1423.822 kb on - strand, within Rv1273cat 1423.822 kb on - strand, within Rv1273cat 1423.886 kb on + strandat 1423.954 kb on - strandat 1424.055 kb on + strandat 1424.056 kb on - strandat 1424.192 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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1,421,320 - Rv1272c 0.48 -2.6
1,421,320 - Rv1272c 0.48 -0.3
1,421,509 + Rv1272c 0.58 -0.8
1,422,358 - -2.8
1,422,567 + Rv1273c 0.15 -2.5
1,422,567 + Rv1273c 0.15 -3.5
1,422,568 - Rv1273c 0.15 +0.3
1,422,568 - Rv1273c 0.15 -1.1
1,422,793 - Rv1273c 0.28 -1.1
1,423,020 + Rv1273c 0.41 -2.6
1,423,213 - Rv1273c 0.52 +0.3
1,423,822 - Rv1273c 0.87 -0.8
1,423,822 - Rv1273c 0.87 -2.3
1,423,822 - Rv1273c 0.87 -2.7
1,423,886 + -3.1
1,423,954 - -3.2
1,424,055 + -1.0
1,424,056 - -0.3
1,424,192 + +0.5

Or see this region's nucleotide sequence