Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1106c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1104 and Rv1105 are separated by 320 nucleotidesRv1105 and Rv1106c are separated by 17 nucleotidesRv1106c and Rv1107c are separated by 9 nucleotidesRv1107c and Rv1108c overlap by 11 nucleotides Rv1104: Rv1104 - Possible para-nitrobenzyl esterase (fragment), at 1,231,301 to 1,231,990 Rv1104 Rv1105: Rv1105 - Possible para-nitrobenzyl esterase (fragment), at 1,232,311 to 1,232,826 Rv1105 Rv1106c: Rv1106c - 3-beta-hydroxysteroid dehydrogenase, at 1,232,844 to 1,233,956 Rv1106c Rv1107c: Rv1107c - Probable exodeoxyribonuclease VII (small subunit) XseB (exonuclease VII small subunit), at 1,233,966 to 1,234,223 Rv1107c Rv1108c: Rv1108c - Probable exodeoxyribonuclease VII (large subunit) XseA (exonuclease VII large subunit), at 1,234,213 to 1,235,460 Rv1108c Position (kb) 1232 1233 1234Strain fitness (log2 ratio) -2 -1 0 1 2at 1231.978 kb on + strandat 1231.979 kb on - strandat 1232.415 kb on + strand, within Rv1105at 1232.488 kb on + strand, within Rv1105at 1232.488 kb on + strand, within Rv1105at 1232.488 kb on + strand, within Rv1105at 1232.489 kb on - strand, within Rv1105at 1232.566 kb on + strand, within Rv1105at 1232.726 kb on - strand, within Rv1105at 1232.836 kb on - strandat 1232.914 kb on + strandat 1232.914 kb on + strandat 1232.914 kb on + strandat 1232.914 kb on + strandat 1232.915 kb on - strandat 1232.915 kb on - strandat 1232.915 kb on - strandat 1232.915 kb on - strandat 1232.917 kb on + strandat 1232.918 kb on - strandat 1232.965 kb on + strand, within Rv1106cat 1232.965 kb on + strand, within Rv1106cat 1232.966 kb on - strand, within Rv1106cat 1233.013 kb on + strand, within Rv1106cat 1233.013 kb on + strand, within Rv1106cat 1233.094 kb on - strand, within Rv1106cat 1233.179 kb on + strand, within Rv1106cat 1233.180 kb on - strand, within Rv1106cat 1233.286 kb on + strand, within Rv1106cat 1233.286 kb on + strand, within Rv1106cat 1233.286 kb on + strand, within Rv1106cat 1233.287 kb on - strand, within Rv1106cat 1233.287 kb on - strand, within Rv1106cat 1233.287 kb on - strand, within Rv1106cat 1233.287 kb on - strand, within Rv1106cat 1233.484 kb on + strand, within Rv1106cat 1233.506 kb on + strand, within Rv1106cat 1233.507 kb on - strand, within Rv1106cat 1233.650 kb on + strand, within Rv1106cat 1233.651 kb on - strand, within Rv1106cat 1234.027 kb on - strand, within Rv1107cat 1234.154 kb on - strand, within Rv1107cat 1234.366 kb on + strand, within Rv1108cat 1234.366 kb on + strand, within Rv1108cat 1234.367 kb on - strand, within Rv1108c

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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1,231,978 + -0.3
1,231,979 - -0.7
1,232,415 + Rv1105 0.20 -0.0
1,232,488 + Rv1105 0.34 -0.5
1,232,488 + Rv1105 0.34 -0.9
1,232,488 + Rv1105 0.34 -1.5
1,232,489 - Rv1105 0.34 -0.2
1,232,566 + Rv1105 0.49 -0.6
1,232,726 - Rv1105 0.80 +0.3
1,232,836 - -0.9
1,232,914 + -0.6
1,232,914 + +0.2
1,232,914 + -0.1
1,232,914 + -0.7
1,232,915 - -0.6
1,232,915 - +0.3
1,232,915 - +0.3
1,232,915 - -0.7
1,232,917 + +0.9
1,232,918 - +1.9
1,232,965 + Rv1106c 0.11 -0.4
1,232,965 + Rv1106c 0.11 -0.7
1,232,966 - Rv1106c 0.11 -0.4
1,233,013 + Rv1106c 0.15 +0.5
1,233,013 + Rv1106c 0.15 -0.3
1,233,094 - Rv1106c 0.22 +1.3
1,233,179 + Rv1106c 0.30 -0.2
1,233,180 - Rv1106c 0.30 +0.0
1,233,286 + Rv1106c 0.40 -0.3
1,233,286 + Rv1106c 0.40 +0.3
1,233,286 + Rv1106c 0.40 -0.8
1,233,287 - Rv1106c 0.40 -0.3
1,233,287 - Rv1106c 0.40 +0.2
1,233,287 - Rv1106c 0.40 -0.9
1,233,287 - Rv1106c 0.40 -0.4
1,233,484 + Rv1106c 0.58 -0.7
1,233,506 + Rv1106c 0.59 -2.4
1,233,507 - Rv1106c 0.60 -0.9
1,233,650 + Rv1106c 0.72 -0.8
1,233,651 - Rv1106c 0.73 -0.3
1,234,027 - Rv1107c 0.24 +0.3
1,234,154 - Rv1107c 0.73 -0.1
1,234,366 + Rv1108c 0.12 -0.2
1,234,366 + Rv1108c 0.12 -1.1
1,234,367 - Rv1108c 0.12 -1.4

Or see this region's nucleotide sequence