Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0543c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0542c and Rv0543c are separated by 68 nucleotidesRv0543c and Rv0544c are separated by 59 nucleotidesRv0544c and Rv0545c overlap by 4 nucleotides Rv0542c: Rv0542c - Possible O-succinylbenzoic acid--CoA ligase MenE (OSB-CoA synthetase) (O-succinylbenzoate-CoA synthase), at 634,416 to 635,504 Rv0542c Rv0543c: Rv0543c - Conserved protein, at 635,573 to 635,875 Rv0543c Rv0544c: Rv0544c - Possible conserved transmembrane protein, at 635,935 to 636,213 Rv0544c Rv0545c: Rv0545c - Probable low-affinity inorganic phosphate transporter integral membrane protein PitA, at 636,210 to 637,463 Rv0545c Position (kb) 635 636Strain fitness (log2 ratio) -1 0 1at 635.882 kb on - strandat 635.882 kb on - strandat 635.882 kb on - strandat 635.884 kb on - strandat 635.936 kb on + strandat 635.999 kb on + strand, within Rv0544cat 635.999 kb on + strand, within Rv0544cat 636.020 kb on - strand, within Rv0544cat 636.195 kb on - strandat 636.195 kb on - strandat 636.195 kb on - strandat 636.763 kb on + strand, within Rv0545cat 636.764 kb on - strand, within Rv0545c

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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635,882 - +0.3
635,882 - +0.1
635,882 - +1.3
635,884 - -0.4
635,936 + -1.5
635,999 + Rv0544c 0.23 +0.6
635,999 + Rv0544c 0.23 +0.8
636,020 - Rv0544c 0.30 +1.1
636,195 - +1.7
636,195 - +1.2
636,195 - +0.1
636,763 + Rv0545c 0.44 +0.8
636,764 - Rv0545c 0.44 +0.7

Or see this region's nucleotide sequence