Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0358

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0357c and Rv0358 are separated by 90 nucleotidesRv0358 and Rv0359 are separated by 10 nucleotidesRv0359 and Rv0360c are separated by 4 nucleotides Rv0357c: Rv0357c - Probable adenylosuccinate synthetase PurA (imp--aspartate ligase) (ADSS) (ampsase), at 435,471 to 436,769 Rv0357c Rv0358: Rv0358 - Conserved protein, at 436,860 to 437,507 Rv0358 Rv0359: Rv0359 - Probable conserved integral membrane protein, at 437,518 to 438,297 Rv0359 Rv0360c: Rv0360c - Conserved protein, at 438,302 to 438,739 Rv0360c Position (kb) 436 437 438Strain fitness (log2 ratio) -1 0 1at 436.798 kb on - strandat 436.830 kb on - strandat 436.830 kb on - strandat 436.830 kb on - strandat 436.863 kb on + strandat 437.642 kb on - strand, within Rv0359at 437.759 kb on - strand, within Rv0359at 437.782 kb on + strand, within Rv0359at 437.863 kb on + strand, within Rv0359at 437.863 kb on + strand, within Rv0359at 437.863 kb on + strand, within Rv0359at 437.864 kb on - strand, within Rv0359at 437.864 kb on - strand, within Rv0359at 437.864 kb on - strand, within Rv0359at 437.864 kb on - strand, within Rv0359at 437.864 kb on - strand, within Rv0359at 438.018 kb on - strand, within Rv0359at 438.018 kb on - strand, within Rv0359at 438.018 kb on - strand, within Rv0359at 438.048 kb on - strand, within Rv0359at 438.048 kb on - strand, within Rv0359at 438.211 kb on + strand, within Rv0359at 438.212 kb on - strand, within Rv0359at 438.285 kb on + strandat 438.285 kb on + strandat 438.366 kb on + strand, within Rv0360cat 438.367 kb on - strand, within Rv0360cat 438.367 kb on - strand, within Rv0360cat 438.423 kb on - strand, within Rv0360c

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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436,798 - -0.6
436,830 - -0.3
436,830 - -0.1
436,830 - +1.3
436,863 + +0.3
437,642 - Rv0359 0.16 +0.4
437,759 - Rv0359 0.31 +0.6
437,782 + Rv0359 0.34 -0.1
437,863 + Rv0359 0.44 -0.2
437,863 + Rv0359 0.44 +0.1
437,863 + Rv0359 0.44 +0.5
437,864 - Rv0359 0.44 +0.4
437,864 - Rv0359 0.44 -0.1
437,864 - Rv0359 0.44 +0.6
437,864 - Rv0359 0.44 +0.2
437,864 - Rv0359 0.44 -0.2
438,018 - Rv0359 0.64 +0.3
438,018 - Rv0359 0.64 -1.2
438,018 - Rv0359 0.64 -0.2
438,048 - Rv0359 0.68 +0.1
438,048 - Rv0359 0.68 -0.0
438,211 + Rv0359 0.89 +0.3
438,212 - Rv0359 0.89 -0.3
438,285 + -0.2
438,285 + +0.3
438,366 + Rv0360c 0.15 -0.4
438,367 - Rv0360c 0.15 -0.2
438,367 - Rv0360c 0.15 -0.7
438,423 - Rv0360c 0.28 +1.2

Or see this region's nucleotide sequence