Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0018c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0017c and Rv0018c overlap by 4 nucleotidesRv0018c and Rv0019c are separated by 88 nucleotidesRv0019c and Rv0020c are separated by 123 nucleotides Rv0017c: Rv0017c - Probable cell division protein RodA, at 20,231 to 21,640 Rv0017c Rv0018c: Rv0018c - Phosphoserine/threonine phosphatase PstP, at 21,637 to 23,181 Rv0018c Rv0019c: Rv0019c - Conserved protein with FHA domain, FhaB, at 23,270 to 23,737 Rv0019c Rv0020c: Rv0020c - Conserved protein with FHA domain, FhaA, at 23,861 to 25,444 Rv0020c Position (kb) 21 22 23 24Strain fitness (log2 ratio) -2 -1 0 1 2at 20.883 kb on + strand, within Rv0017cat 20.884 kb on - strand, within Rv0017cat 21.415 kb on - strand, within Rv0017cat 22.118 kb on + strand, within Rv0018cat 22.119 kb on - strand, within Rv0018cat 22.187 kb on + strand, within Rv0018cat 22.455 kb on - strand, within Rv0018cat 23.382 kb on - strand, within Rv0019cat 23.382 kb on - strand, within Rv0019cat 23.443 kb on - strand, within Rv0019cat 23.443 kb on - strand, within Rv0019cat 23.513 kb on - strand, within Rv0019cat 23.641 kb on - strand, within Rv0019cat 23.856 kb on + strandat 23.857 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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20,883 + Rv0017c 0.46 +0.3
20,884 - Rv0017c 0.46 -1.9
21,415 - Rv0017c 0.84 -1.1
22,118 + Rv0018c 0.31 -0.7
22,119 - Rv0018c 0.31 -1.8
22,187 + Rv0018c 0.36 +1.9
22,455 - Rv0018c 0.53 -1.3
23,382 - Rv0019c 0.24 +0.9
23,382 - Rv0019c 0.24 -0.1
23,443 - Rv0019c 0.37 +1.3
23,443 - Rv0019c 0.37 +0.1
23,513 - Rv0019c 0.52 -1.1
23,641 - Rv0019c 0.79 -0.5
23,856 + -1.0
23,857 - +0.3

Or see this region's nucleotide sequence