Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2846c

Experiment: Stearic 100 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2845c and Rv2846c are separated by 88 nucleotidesRv2846c and Rv2847c are separated by 22 nucleotides Rv2845c: Rv2845c - Probable prolyl-tRNA synthetase ProS (proline--tRNA ligase) (PRORS) (global RNA synthesis factor) (proline translase), at 3,151,202 to 3,152,950 Rv2845c Rv2846c: Rv2846c - Possible integral membrane efflux protein EfpA, at 3,153,039 to 3,154,631 Rv2846c Rv2847c: Rv2847c - Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase, at 3,154,654 to 3,155,871 Rv2847c Position (kb) 3153 3154 3155Strain fitness (log2 ratio) -1 0 1at 3152.963 kb on + strandat 3152.963 kb on + strandat 3154.645 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Stearic 100 uM (C)
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3,152,963 + +1.3
3,152,963 + -0.6
3,154,645 - -0.3

Or see this region's nucleotide sequence