Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3340

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3339c and Rv3340 are separated by 282 nucleotidesRv3340 and Rv3341 are separated by 11 nucleotides Rv3339c: Rv3339c - Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP), at 3,724,615 to 3,725,844 Rv3339c Rv3340: Rv3340 - Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetylhomoserine (thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase), at 3,726,127 to 3,727,476 Rv3340 Rv3341: Rv3341 - Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA), at 3,727,488 to 3,728,627 Rv3341 Position (kb) 3726 3727 3728Strain fitness (log2 ratio) -2 -1 0 1at 3725.144 kb on + strand, within Rv3339cat 3725.213 kb on + strand, within Rv3339cat 3725.213 kb on + strand, within Rv3339cat 3725.213 kb on + strand, within Rv3339cat 3725.214 kb on - strand, within Rv3339cat 3725.214 kb on - strand, within Rv3339cat 3725.214 kb on - strand, within Rv3339cat 3725.216 kb on - strand, within Rv3339cat 3725.289 kb on - strand, within Rv3339cat 3725.289 kb on - strand, within Rv3339cat 3725.420 kb on + strand, within Rv3339cat 3725.712 kb on - strand, within Rv3339cat 3725.712 kb on - strand, within Rv3339cat 3725.803 kb on + strandat 3725.824 kb on + strandat 3725.865 kb on + strandat 3725.866 kb on - strandat 3725.866 kb on - strandat 3725.885 kb on + strandat 3725.944 kb on + strandat 3725.945 kb on - strandat 3725.945 kb on - strandat 3726.058 kb on + strandat 3726.502 kb on + strand, within Rv3340at 3727.111 kb on + strand, within Rv3340at 3727.111 kb on + strand, within Rv3340at 3727.111 kb on + strand, within Rv3340at 3727.389 kb on + strandat 3727.504 kb on + strandat 3727.504 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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3,725,144 + Rv3339c 0.43 -0.5
3,725,213 + Rv3339c 0.49 +0.1
3,725,213 + Rv3339c 0.49 -0.9
3,725,213 + Rv3339c 0.49 -0.4
3,725,214 - Rv3339c 0.49 -0.3
3,725,214 - Rv3339c 0.49 -0.5
3,725,214 - Rv3339c 0.49 -1.1
3,725,216 - Rv3339c 0.49 -0.2
3,725,289 - Rv3339c 0.55 -0.4
3,725,289 - Rv3339c 0.55 +0.1
3,725,420 + Rv3339c 0.65 -0.8
3,725,712 - Rv3339c 0.89 -0.1
3,725,712 - Rv3339c 0.89 -0.8
3,725,803 + -0.4
3,725,824 + +1.1
3,725,865 + -1.1
3,725,866 - -0.3
3,725,866 - +0.1
3,725,885 + -0.7
3,725,944 + +0.5
3,725,945 - -1.4
3,725,945 - -0.6
3,726,058 + -2.4
3,726,502 + Rv3340 0.28 -0.8
3,727,111 + Rv3340 0.73 +0.3
3,727,111 + Rv3340 0.73 -0.2
3,727,111 + Rv3340 0.73 -1.3
3,727,389 + -0.6
3,727,504 + -1.0
3,727,504 + -1.4

Or see this region's nucleotide sequence