Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3207c

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3206c and Rv3207c are separated by 90 nucleotidesRv3207c and Rv3208 are separated by 345 nucleotides Rv3206c: Rv3206c - Probable molybdenum cofactor biosynthesis protein MoeB1 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase), at 3,582,532 to 3,583,710 Rv3206c Rv3207c: Rv3207c - Conserved protein, at 3,583,801 to 3,584,658 Rv3207c Rv3208: Rv3208 - Probable transcriptional regulatory protein (probably TetR-family), at 3,585,004 to 3,585,690 Rv3208 Position (kb) 3583 3584 3585Strain fitness (log2 ratio) -1 0 1 2at 3583.727 kb on + strandat 3583.728 kb on - strandat 3584.000 kb on + strand, within Rv3207cat 3584.001 kb on - strand, within Rv3207cat 3584.017 kb on + strand, within Rv3207cat 3584.018 kb on - strand, within Rv3207cat 3584.018 kb on - strand, within Rv3207cat 3584.111 kb on + strand, within Rv3207cat 3584.111 kb on + strand, within Rv3207cat 3584.340 kb on - strand, within Rv3207cat 3584.592 kb on - strandat 3584.649 kb on - strandat 3584.792 kb on - strandat 3584.923 kb on + strandat 3584.926 kb on + strandat 3584.926 kb on + strandat 3584.926 kb on + strandat 3584.927 kb on - strandat 3584.927 kb on - strandat 3584.927 kb on - strandat 3584.981 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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3,583,727 + +2.2
3,583,728 - -0.3
3,584,000 + Rv3207c 0.23 +0.6
3,584,001 - Rv3207c 0.23 +1.1
3,584,017 + Rv3207c 0.25 +2.5
3,584,018 - Rv3207c 0.25 +0.7
3,584,018 - Rv3207c 0.25 +1.0
3,584,111 + Rv3207c 0.36 +2.1
3,584,111 + Rv3207c 0.36 +1.2
3,584,340 - Rv3207c 0.63 +1.0
3,584,592 - +0.9
3,584,649 - +0.3
3,584,792 - +0.8
3,584,923 + -0.6
3,584,926 + +1.0
3,584,926 + +0.3
3,584,926 + -0.0
3,584,927 - -0.5
3,584,927 - -0.0
3,584,927 - -0.1
3,584,981 + -0.5

Or see this region's nucleotide sequence