Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1638A

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1638 and Rv1638A are separated by 56 nucleotidesRv1638A and Rv1639c are separated by 15 nucleotides Rv1638: Rv1638 - Probable excinuclease ABC (subunit A-DNA-binding ATPase) UvrA, at 1,843,741 to 1,846,659 Rv1638 Rv1638A: Rv1638A - Conserved hypothetical protein, at 1,846,716 to 1,846,973 Rv1638A Rv1639c: Rv1639c - Conserved hypothetical membrane protein, at 1,846,989 to 1,848,458 Rv1639c Position (kb) 1846 1847Strain fitness (log2 ratio) -2 -1 0 1at 1845.890 kb on - strand, within Rv1638at 1846.058 kb on - strand, within Rv1638at 1846.117 kb on + strand, within Rv1638at 1846.118 kb on - strand, within Rv1638at 1846.118 kb on - strand, within Rv1638at 1846.204 kb on + strand, within Rv1638at 1846.205 kb on - strand, within Rv1638at 1846.208 kb on + strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.209 kb on - strand, within Rv1638at 1846.237 kb on + strand, within Rv1638at 1846.340 kb on - strand, within Rv1638at 1846.382 kb on + strandat 1846.382 kb on + strandat 1846.382 kb on + strandat 1846.428 kb on + strandat 1846.449 kb on + strandat 1846.990 kb on + strandat 1847.324 kb on - strand, within Rv1639cat 1847.324 kb on - strand, within Rv1639cat 1847.462 kb on + strand, within Rv1639cat 1847.576 kb on - strand, within Rv1639cat 1847.674 kb on - strand, within Rv1639cat 1847.858 kb on - strand, within Rv1639c

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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1,845,890 - Rv1638 0.74 +0.6
1,846,058 - Rv1638 0.79 -1.0
1,846,117 + Rv1638 0.81 +0.5
1,846,118 - Rv1638 0.81 -0.6
1,846,118 - Rv1638 0.81 -2.0
1,846,204 + Rv1638 0.84 -0.0
1,846,205 - Rv1638 0.84 -0.7
1,846,208 + Rv1638 0.85 +0.5
1,846,209 - Rv1638 0.85 +0.5
1,846,209 - Rv1638 0.85 +0.4
1,846,209 - Rv1638 0.85 -0.5
1,846,209 - Rv1638 0.85 +0.1
1,846,209 - Rv1638 0.85 -0.5
1,846,237 + Rv1638 0.86 -2.0
1,846,340 - Rv1638 0.89 -0.8
1,846,382 + +0.5
1,846,382 + -0.4
1,846,382 + +0.0
1,846,428 + -1.0
1,846,449 + -1.3
1,846,990 + -2.7
1,847,324 - Rv1639c 0.23 +0.7
1,847,324 - Rv1639c 0.23 -0.4
1,847,462 + Rv1639c 0.32 -1.1
1,847,576 - Rv1639c 0.40 -0.5
1,847,674 - Rv1639c 0.47 +0.7
1,847,858 - Rv1639c 0.59 +0.2

Or see this region's nucleotide sequence