Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0778

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0777 and Rv0778 are separated by 4 nucleotidesRv0778 and Rv0779c overlap by 4 nucleotidesRv0779c and Rv0780 are separated by 50 nucleotides Rv0777: Rv0777 - Probable adenylosuccinate lyase PurB (adenylosuccinase) (ASL) (ASASE), at 870,008 to 871,426 Rv0777 Rv0778: Rv0778 - Possible cytochrome P450 126 Cyp126, at 871,431 to 872,675 Rv0778 Rv0779c: Rv0779c - Possible conserved transmembrane protein, at 872,672 to 873,292 Rv0779c Rv0780: Rv0780 - Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC (SAICAR synthetase), at 873,343 to 874,236 Rv0780 Position (kb) 871 872 873Strain fitness (log2 ratio) -1 0 1at 871.436 kb on + strandat 871.540 kb on - strandat 871.638 kb on + strand, within Rv0778at 871.639 kb on - strand, within Rv0778at 871.840 kb on + strand, within Rv0778at 871.840 kb on + strand, within Rv0778at 872.037 kb on + strand, within Rv0778at 872.038 kb on - strand, within Rv0778at 872.043 kb on + strand, within Rv0778at 872.043 kb on + strand, within Rv0778at 872.044 kb on - strand, within Rv0778at 872.067 kb on - strand, within Rv0778at 872.160 kb on + strand, within Rv0778at 872.160 kb on + strand, within Rv0778at 872.161 kb on - strand, within Rv0778at 872.621 kb on + strandat 872.674 kb on - strandat 873.301 kb on + strandat 873.302 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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871,436 + +1.1
871,540 - -0.2
871,638 + Rv0778 0.17 -0.1
871,639 - Rv0778 0.17 -0.4
871,840 + Rv0778 0.33 +0.2
871,840 + Rv0778 0.33 -0.4
872,037 + Rv0778 0.49 +1.0
872,038 - Rv0778 0.49 -0.3
872,043 + Rv0778 0.49 -0.3
872,043 + Rv0778 0.49 -1.0
872,044 - Rv0778 0.49 -0.8
872,067 - Rv0778 0.51 -0.0
872,160 + Rv0778 0.59 -0.5
872,160 + Rv0778 0.59 -1.3
872,161 - Rv0778 0.59 -0.1
872,621 + +0.5
872,674 - -0.1
873,301 + -0.6
873,302 - -0.8

Or see this region's nucleotide sequence