Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3677c

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3675 and Rv3676 are separated by 98 nucleotidesRv3676 and Rv3677c are separated by 105 nucleotidesRv3677c and Rv3678c are separated by 6 nucleotidesRv3678c and Rv3678A are separated by 15 nucleotidesRv3678A and Rv3679 are separated by 84 nucleotides Rv3675: Rv3675 - Possible membrane protein, at 4,116,002 to 4,116,379 Rv3675 Rv3676: Rv3676 - Transcriptional regulatory protein Crp (Crp/Fnr-family), at 4,116,478 to 4,117,152 Rv3676 Rv3677c: Rv3677c - Possible hydrolase, at 4,117,258 to 4,118,052 Rv3677c Rv3678c: Rv3678c - Conserved protein, at 4,118,059 to 4,118,514 Rv3678c Rv3678A: Rv3678A - Conserved hypothetical protein, at 4,118,530 to 4,118,691 Rv3678A Rv3679: Rv3679 - Probable anion transporter ATPase, at 4,118,776 to 4,119,798 Rv3679 Position (kb) 4117 4118 4119Strain fitness (log2 ratio) -1 0 1 2at 4116.304 kb on + strand, within Rv3675at 4116.405 kb on + strandat 4116.447 kb on + strandat 4117.184 kb on + strandat 4117.185 kb on - strandat 4117.185 kb on - strandat 4117.275 kb on - strandat 4117.399 kb on + strand, within Rv3677cat 4117.399 kb on + strand, within Rv3677cat 4117.400 kb on - strand, within Rv3677cat 4117.532 kb on + strand, within Rv3677cat 4117.532 kb on + strand, within Rv3677cat 4117.532 kb on + strand, within Rv3677cat 4117.533 kb on - strand, within Rv3677cat 4117.540 kb on + strand, within Rv3677cat 4117.665 kb on + strand, within Rv3677cat 4117.666 kb on - strand, within Rv3677cat 4118.108 kb on - strand, within Rv3678cat 4118.445 kb on - strand, within Rv3678cat 4118.524 kb on + strandat 4118.525 kb on - strandat 4118.532 kb on - strandat 4118.532 kb on - strandat 4118.549 kb on + strand, within Rv3678Aat 4118.666 kb on + strand, within Rv3678Aat 4118.666 kb on + strand, within Rv3678Aat 4118.703 kb on - strandat 4118.767 kb on + strandat 4118.767 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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4,116,304 + Rv3675 0.80 -0.1
4,116,405 + +0.5
4,116,447 + +1.2
4,117,184 + -0.6
4,117,185 - -1.0
4,117,185 - -1.6
4,117,275 - +0.3
4,117,399 + Rv3677c 0.18 -1.7
4,117,399 + Rv3677c 0.18 -1.6
4,117,400 - Rv3677c 0.18 -0.2
4,117,532 + Rv3677c 0.34 -0.2
4,117,532 + Rv3677c 0.34 +0.2
4,117,532 + Rv3677c 0.34 -0.6
4,117,533 - Rv3677c 0.35 -0.6
4,117,540 + Rv3677c 0.35 -1.0
4,117,665 + Rv3677c 0.51 +1.8
4,117,666 - Rv3677c 0.51 +0.2
4,118,108 - Rv3678c 0.11 +0.7
4,118,445 - Rv3678c 0.85 +0.6
4,118,524 + +1.8
4,118,525 - +0.1
4,118,532 - -0.2
4,118,532 - +2.0
4,118,549 + Rv3678A 0.12 +1.2
4,118,666 + Rv3678A 0.84 +0.3
4,118,666 + Rv3678A 0.84 -0.2
4,118,703 - +0.8
4,118,767 + -0.3
4,118,767 + -0.6

Or see this region's nucleotide sequence