Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2854

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2853 and Rv2854 are separated by 36 nucleotidesRv2854 and Rv2855 are separated by 12 nucleotides Rv2853: Rv2853 - PE-PGRS family protein PE_PGRS48, at 3,162,268 to 3,164,115 Rv2853 Rv2854: Rv2854 - Unknown protein, at 3,164,152 to 3,165,192 Rv2854 Rv2855: Rv2855 - NADPH-dependent mycothiol reductase Mtr, at 3,165,205 to 3,166,584 Rv2855 Position (kb) 3164 3165 3166Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3163.164 kb on + strand, within Rv2853at 3163.267 kb on - strand, within Rv2853at 3163.676 kb on + strand, within Rv2853at 3163.677 kb on - strand, within Rv2853at 3163.809 kb on + strand, within Rv2853at 3164.049 kb on + strandat 3164.049 kb on + strandat 3164.050 kb on - strandat 3164.050 kb on - strandat 3164.140 kb on + strandat 3164.140 kb on + strandat 3164.329 kb on + strand, within Rv2854at 3164.471 kb on - strand, within Rv2854at 3164.538 kb on - strand, within Rv2854at 3164.539 kb on + strand, within Rv2854at 3164.540 kb on - strand, within Rv2854at 3164.785 kb on + strand, within Rv2854at 3164.786 kb on - strand, within Rv2854at 3164.804 kb on - strand, within Rv2854at 3164.885 kb on + strand, within Rv2854at 3165.497 kb on - strand, within Rv2855at 3165.624 kb on - strand, within Rv2855

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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3,163,164 + Rv2853 0.48 -0.6
3,163,267 - Rv2853 0.54 -0.4
3,163,676 + Rv2853 0.76 -1.9
3,163,677 - Rv2853 0.76 -0.2
3,163,809 + Rv2853 0.83 -0.1
3,164,049 + +2.8
3,164,049 + +1.0
3,164,050 - -0.4
3,164,050 - +0.0
3,164,140 + +0.4
3,164,140 + +0.1
3,164,329 + Rv2854 0.17 -1.2
3,164,471 - Rv2854 0.31 -0.1
3,164,538 - Rv2854 0.37 -0.6
3,164,539 + Rv2854 0.37 +0.0
3,164,540 - Rv2854 0.37 -0.7
3,164,785 + Rv2854 0.61 -0.2
3,164,786 - Rv2854 0.61 +0.8
3,164,804 - Rv2854 0.63 +0.8
3,164,885 + Rv2854 0.70 -0.8
3,165,497 - Rv2855 0.21 -0.3
3,165,624 - Rv2855 0.30 -1.3

Or see this region's nucleotide sequence