Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2062c

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2059 and Rv2060 overlap by 431 nucleotidesRv2060 and Rv2061c are separated by 0 nucleotidesRv2061c and Rv2062c are separated by 83 nucleotidesRv2062c and Rv2063 are separated by 77 nucleotidesRv2063 and Rv2063A overlap by 8 nucleotidesRv2063A and Rv2064 overlap by 17 nucleotides Rv2059: Rv2059 - Conserved hypothetical protein, at 2,315,174 to 2,316,709 Rv2059 Rv2060: Rv2060 - Possible conserved integral membrane protein, at 2,316,279 to 2,316,680 Rv2060 Rv2061c: Rv2061c - Conserved protein, at 2,316,681 to 2,317,085 Rv2061c Rv2062c: Rv2062c - Cobalamin biosynthesis protein CobN, at 2,317,169 to 2,320,753 Rv2062c Rv2063: Rv2063 - Antitoxin MazE7, at 2,320,831 to 2,321,064 Rv2063 Rv2063A: Rv2063A - Possible toxin MazF7, at 2,321,057 to 2,321,467 Rv2063A Rv2064: Rv2064 - Precorrin-3B synthase CobG, at 2,321,451 to 2,322,542 Rv2064 Position (kb) 2317 2318 2319 2320 2321Strain fitness (log2 ratio) -2 -1 0 1 2at 2316.327 kb on + strandat 2316.431 kb on - strandat 2316.646 kb on - strandat 2316.678 kb on + strandat 2316.749 kb on + strand, within Rv2061cat 2316.749 kb on + strand, within Rv2061cat 2316.750 kb on - strand, within Rv2061cat 2316.805 kb on + strand, within Rv2061cat 2317.049 kb on - strandat 2317.077 kb on - strandat 2317.098 kb on - strandat 2317.347 kb on + strandat 2317.368 kb on + strandat 2317.368 kb on + strandat 2317.369 kb on - strandat 2317.416 kb on + strandat 2317.452 kb on + strandat 2317.575 kb on + strand, within Rv2062cat 2317.575 kb on + strand, within Rv2062cat 2317.641 kb on + strand, within Rv2062cat 2317.641 kb on + strand, within Rv2062cat 2317.785 kb on + strand, within Rv2062cat 2318.426 kb on + strand, within Rv2062cat 2319.301 kb on - strand, within Rv2062cat 2319.444 kb on + strand, within Rv2062cat 2319.847 kb on - strand, within Rv2062cat 2319.847 kb on - strand, within Rv2062cat 2320.279 kb on - strand, within Rv2062cat 2320.443 kb on + strandat 2320.443 kb on + strandat 2320.444 kb on - strandat 2320.444 kb on - strandat 2320.444 kb on - strandat 2320.824 kb on + strandat 2321.163 kb on + strand, within Rv2063Aat 2321.163 kb on + strand, within Rv2063Aat 2321.263 kb on - strand, within Rv2063Aat 2321.729 kb on + strand, within Rv2064

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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2,316,327 + -1.4
2,316,431 - -0.3
2,316,646 - +2.2
2,316,678 + -0.3
2,316,749 + Rv2061c 0.17 -0.1
2,316,749 + Rv2061c 0.17 -0.2
2,316,750 - Rv2061c 0.17 +0.3
2,316,805 + Rv2061c 0.31 -0.0
2,317,049 - +0.8
2,317,077 - -0.3
2,317,098 - -0.6
2,317,347 + +0.1
2,317,368 + -0.3
2,317,368 + -0.1
2,317,369 - +0.7
2,317,416 + +1.7
2,317,452 + -0.3
2,317,575 + Rv2062c 0.11 +0.4
2,317,575 + Rv2062c 0.11 -1.1
2,317,641 + Rv2062c 0.13 +0.7
2,317,641 + Rv2062c 0.13 -0.5
2,317,785 + Rv2062c 0.17 -0.3
2,318,426 + Rv2062c 0.35 -0.1
2,319,301 - Rv2062c 0.59 -1.0
2,319,444 + Rv2062c 0.63 -1.3
2,319,847 - Rv2062c 0.75 +0.5
2,319,847 - Rv2062c 0.75 -0.5
2,320,279 - Rv2062c 0.87 -1.1
2,320,443 + -0.5
2,320,443 + -0.2
2,320,444 - -1.9
2,320,444 - -0.2
2,320,444 - -0.6
2,320,824 + -1.3
2,321,163 + Rv2063A 0.26 -1.0
2,321,163 + Rv2063A 0.26 -0.1
2,321,263 - Rv2063A 0.50 -0.6
2,321,729 + Rv2064 0.25 -0.3

Or see this region's nucleotide sequence