Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1193

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1191 and Rv1192 are separated by 81 nucleotidesRv1192 and Rv1193 are separated by 39 nucleotidesRv1193 and Rv1194c are separated by 32 nucleotides Rv1191: Rv1191 - Conserved protein, at 1,333,931 to 1,334,845 Rv1191 Rv1192: Rv1192 - Unknown protein, at 1,334,927 to 1,335,754 Rv1192 Rv1193: Rv1193 - Probable fatty-acid-CoA ligase FadD36 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 1,335,794 to 1,337,215 Rv1193 Rv1194c: Rv1194c - Conserved protein, at 1,337,248 to 1,338,513 Rv1194c Position (kb) 1335 1336 1337 1338Strain fitness (log2 ratio) -2 -1 0 1at 1334.907 kb on - strandat 1334.918 kb on + strandat 1334.918 kb on + strandat 1334.919 kb on - strandat 1334.919 kb on - strandat 1334.921 kb on + strandat 1334.921 kb on + strandat 1334.922 kb on - strandat 1334.922 kb on - strandat 1334.922 kb on - strandat 1334.943 kb on + strandat 1334.987 kb on + strandat 1334.988 kb on - strandat 1334.988 kb on - strandat 1335.021 kb on - strand, within Rv1192at 1335.094 kb on - strand, within Rv1192at 1335.497 kb on + strand, within Rv1192at 1335.709 kb on + strandat 1336.199 kb on + strand, within Rv1193at 1336.332 kb on - strand, within Rv1193at 1336.437 kb on - strand, within Rv1193at 1336.437 kb on - strand, within Rv1193at 1336.617 kb on - strand, within Rv1193at 1337.058 kb on + strand, within Rv1193at 1337.151 kb on + strandat 1337.152 kb on - strandat 1337.265 kb on + strandat 1337.288 kb on - strandat 1337.318 kb on - strandat 1337.409 kb on + strand, within Rv1194cat 1337.409 kb on + strand, within Rv1194cat 1337.867 kb on + strand, within Rv1194c

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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1,334,907 - -0.1
1,334,918 + -0.3
1,334,918 + +0.1
1,334,919 - -0.5
1,334,919 - +0.5
1,334,921 + -0.1
1,334,921 + +0.1
1,334,922 - -0.2
1,334,922 - -0.1
1,334,922 - -0.0
1,334,943 + +0.2
1,334,987 + -0.6
1,334,988 - -0.1
1,334,988 - -0.2
1,335,021 - Rv1192 0.11 -0.4
1,335,094 - Rv1192 0.20 -0.9
1,335,497 + Rv1192 0.69 +0.2
1,335,709 + +0.6
1,336,199 + Rv1193 0.28 -0.7
1,336,332 - Rv1193 0.38 -0.9
1,336,437 - Rv1193 0.45 -1.2
1,336,437 - Rv1193 0.45 -0.3
1,336,617 - Rv1193 0.58 -1.4
1,337,058 + Rv1193 0.89 -1.2
1,337,151 + -0.7
1,337,152 - -0.6
1,337,265 + +0.4
1,337,288 - -0.0
1,337,318 - -0.0
1,337,409 + Rv1194c 0.13 -0.2
1,337,409 + Rv1194c 0.13 +0.8
1,337,867 + Rv1194c 0.49 -2.7

Or see this region's nucleotide sequence