Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0464c

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0462 and Rv0463 are separated by 7 nucleotidesRv0463 and Rv0464c are separated by 3 nucleotidesRv0464c and Rv0465c overlap by 4 nucleotides Rv0462: Rv0462 - Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphorase), at 552,614 to 554,008 Rv0462 Rv0463: Rv0463 - Probable conserved membrane protein, at 554,016 to 554,309 Rv0463 Rv0464c: Rv0464c - Conserved protein, at 554,313 to 554,885 Rv0464c Rv0465c: Rv0465c - Probable transcriptional regulatory protein, at 554,882 to 556,306 Rv0465c Position (kb) 554 555Strain fitness (log2 ratio) -2 -1 0 1 2at 554.085 kb on + strand, within Rv0463at 554.085 kb on + strand, within Rv0463at 554.085 kb on + strand, within Rv0463at 554.086 kb on - strand, within Rv0463at 554.159 kb on - strand, within Rv0463at 554.159 kb on - strand, within Rv0463at 554.301 kb on + strandat 554.314 kb on + strandat 554.315 kb on - strandat 554.315 kb on - strandat 554.487 kb on + strand, within Rv0464cat 554.584 kb on - strand, within Rv0464cat 554.641 kb on - strand, within Rv0464cat 554.713 kb on + strand, within Rv0464cat 554.713 kb on + strand, within Rv0464cat 554.737 kb on + strand, within Rv0464cat 554.737 kb on + strand, within Rv0464cat 554.738 kb on - strand, within Rv0464cat 554.885 kb on + strandat 554.885 kb on + strandat 554.886 kb on - strandat 554.886 kb on - strandat 555.011 kb on - strandat 555.026 kb on - strand, within Rv0465cat 555.026 kb on - strand, within Rv0465cat 555.061 kb on - strand, within Rv0465cat 555.116 kb on - strand, within Rv0465cat 555.129 kb on + strand, within Rv0465cat 555.171 kb on + strand, within Rv0465cat 555.371 kb on + strand, within Rv0465cat 555.371 kb on + strand, within Rv0465cat 555.372 kb on - strand, within Rv0465cat 555.372 kb on - strand, within Rv0465cat 555.372 kb on - strand, within Rv0465cat 555.403 kb on - strand, within Rv0465cat 555.414 kb on + strand, within Rv0465cat 555.415 kb on - strand, within Rv0465cat 555.505 kb on - strand, within Rv0465cat 555.505 kb on - strand, within Rv0465cat 555.505 kb on - strand, within Rv0465cat 555.508 kb on + strand, within Rv0465cat 555.509 kb on - strand, within Rv0465cat 555.600 kb on + strand, within Rv0465cat 555.601 kb on - strand, within Rv0465cat 555.731 kb on + strand, within Rv0465cat 555.732 kb on - strand, within Rv0465cat 555.732 kb on - strand, within Rv0465cat 555.836 kb on + strand, within Rv0465cat 555.837 kb on - strand, within Rv0465cat 555.837 kb on - strand, within Rv0465cat 555.837 kb on - strand, within Rv0465cat 555.837 kb on - strand, within Rv0465cat 555.840 kb on + strand, within Rv0465cat 555.855 kb on + strand, within Rv0465cat 555.855 kb on + strand, within Rv0465cat 555.855 kb on + strand, within Rv0465cat 555.855 kb on + strand, within Rv0465cat 555.856 kb on - strand, within Rv0465cat 555.856 kb on - strand, within Rv0465cat 555.861 kb on + strand, within Rv0465cat 555.861 kb on + strand, within Rv0465cat 555.861 kb on + strand, within Rv0465cat 555.862 kb on - strand, within Rv0465c

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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554,085 + Rv0463 0.23 -0.2
554,085 + Rv0463 0.23 -0.9
554,085 + Rv0463 0.23 +0.5
554,086 - Rv0463 0.24 +0.6
554,159 - Rv0463 0.49 -0.6
554,159 - Rv0463 0.49 +0.1
554,301 + -0.7
554,314 + -0.1
554,315 - +0.3
554,315 - -0.2
554,487 + Rv0464c 0.30 -0.9
554,584 - Rv0464c 0.47 -1.1
554,641 - Rv0464c 0.57 +0.8
554,713 + Rv0464c 0.70 -0.7
554,713 + Rv0464c 0.70 +0.3
554,737 + Rv0464c 0.74 -1.1
554,737 + Rv0464c 0.74 -1.1
554,738 - Rv0464c 0.74 +0.9
554,885 + -1.0
554,885 + -1.4
554,886 - -0.5
554,886 - -0.1
555,011 - +1.8
555,026 - Rv0465c 0.10 -0.7
555,026 - Rv0465c 0.10 +0.0
555,061 - Rv0465c 0.13 +0.3
555,116 - Rv0465c 0.16 +0.1
555,129 + Rv0465c 0.17 -1.3
555,171 + Rv0465c 0.20 -0.7
555,371 + Rv0465c 0.34 -0.2
555,371 + Rv0465c 0.34 -0.2
555,372 - Rv0465c 0.34 -0.2
555,372 - Rv0465c 0.34 -0.3
555,372 - Rv0465c 0.34 -0.5
555,403 - Rv0465c 0.37 -0.1
555,414 + Rv0465c 0.37 -0.9
555,415 - Rv0465c 0.37 -0.3
555,505 - Rv0465c 0.44 -0.4
555,505 - Rv0465c 0.44 -0.8
555,505 - Rv0465c 0.44 +0.2
555,508 + Rv0465c 0.44 +0.4
555,509 - Rv0465c 0.44 -0.4
555,600 + Rv0465c 0.50 -0.3
555,601 - Rv0465c 0.50 -0.5
555,731 + Rv0465c 0.60 -0.0
555,732 - Rv0465c 0.60 -1.2
555,732 - Rv0465c 0.60 -0.3
555,836 + Rv0465c 0.67 +2.2
555,837 - Rv0465c 0.67 +1.1
555,837 - Rv0465c 0.67 -1.6
555,837 - Rv0465c 0.67 +0.1
555,837 - Rv0465c 0.67 -0.9
555,840 + Rv0465c 0.67 -0.2
555,855 + Rv0465c 0.68 -1.1
555,855 + Rv0465c 0.68 +0.7
555,855 + Rv0465c 0.68 +1.1
555,855 + Rv0465c 0.68 -0.2
555,856 - Rv0465c 0.68 +0.1
555,856 - Rv0465c 0.68 +1.8
555,861 + Rv0465c 0.69 -0.4
555,861 + Rv0465c 0.69 -0.3
555,861 + Rv0465c 0.69 -0.7
555,862 - Rv0465c 0.69 -2.2

Or see this region's nucleotide sequence