Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0293c

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0291 and Rv0292 overlap by 4 nucleotidesRv0292 and Rv0293c overlap by 14 nucleotidesRv0293c and Rv0294 are separated by 106 nucleotidesRv0294 and Rv0295c overlap by 12 nucleotides Rv0291: Rv0291 - Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3), at 354,498 to 355,883 Rv0291 Rv0292: Rv0292 - ESX conserved component EccE3. ESX-3 type VII secretion system protein. Probable transmembrane protein., at 355,880 to 356,875 Rv0292 Rv0293c: Rv0293c - Conserved protein, at 356,862 to 358,064 Rv0293c Rv0294: Rv0294 - Probable trans-aconitate methyltransferase Tam, at 358,171 to 358,956 Rv0294 Rv0295c: Rv0295c - Conserved protein, at 358,945 to 359,748 Rv0295c Position (kb) 356 357 358 359Strain fitness (log2 ratio) -2 -1 0 1 2 3at 356.818 kb on + strandat 356.818 kb on + strandat 356.818 kb on + strandat 357.050 kb on + strand, within Rv0293cat 357.050 kb on + strand, within Rv0293cat 357.054 kb on + strand, within Rv0293cat 357.055 kb on - strand, within Rv0293cat 357.085 kb on + strand, within Rv0293cat 357.152 kb on + strand, within Rv0293cat 357.153 kb on - strand, within Rv0293cat 357.153 kb on - strand, within Rv0293cat 357.259 kb on + strand, within Rv0293cat 357.275 kb on + strand, within Rv0293cat 357.275 kb on + strand, within Rv0293cat 357.276 kb on - strand, within Rv0293cat 357.340 kb on + strand, within Rv0293cat 357.340 kb on + strand, within Rv0293cat 357.452 kb on - strand, within Rv0293cat 357.481 kb on + strand, within Rv0293cat 357.517 kb on + strand, within Rv0293cat 357.518 kb on - strand, within Rv0293cat 357.554 kb on + strand, within Rv0293cat 357.555 kb on - strand, within Rv0293cat 357.844 kb on - strand, within Rv0293cat 358.168 kb on + strandat 358.168 kb on + strandat 358.168 kb on + strandat 358.168 kb on + strandat 358.168 kb on + strandat 358.169 kb on - strandat 358.169 kb on - strandat 358.169 kb on - strandat 358.169 kb on - strandat 358.307 kb on - strand, within Rv0294at 358.619 kb on + strand, within Rv0294at 358.726 kb on + strand, within Rv0294at 358.727 kb on - strand, within Rv0294at 358.884 kb on + strandat 358.885 kb on - strandat 358.955 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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356,818 + -0.5
356,818 + +0.1
356,818 + -0.3
357,050 + Rv0293c 0.16 -0.1
357,050 + Rv0293c 0.16 -0.1
357,054 + Rv0293c 0.16 -0.5
357,055 - Rv0293c 0.16 -0.3
357,085 + Rv0293c 0.19 -0.8
357,152 + Rv0293c 0.24 -2.2
357,153 - Rv0293c 0.24 -0.2
357,153 - Rv0293c 0.24 -0.8
357,259 + Rv0293c 0.33 -0.3
357,275 + Rv0293c 0.34 -1.3
357,275 + Rv0293c 0.34 +1.0
357,276 - Rv0293c 0.34 -0.2
357,340 + Rv0293c 0.40 +0.0
357,340 + Rv0293c 0.40 +0.8
357,452 - Rv0293c 0.49 -0.2
357,481 + Rv0293c 0.51 -1.3
357,517 + Rv0293c 0.54 +1.2
357,518 - Rv0293c 0.55 -0.2
357,554 + Rv0293c 0.58 -2.3
357,555 - Rv0293c 0.58 -1.7
357,844 - Rv0293c 0.82 -0.2
358,168 + -0.0
358,168 + +2.8
358,168 + +0.5
358,168 + -0.3
358,168 + -0.5
358,169 - -2.2
358,169 - +0.8
358,169 - -0.2
358,169 - -0.6
358,307 - Rv0294 0.17 -0.2
358,619 + Rv0294 0.57 -0.4
358,726 + Rv0294 0.71 -0.2
358,727 - Rv0294 0.71 +0.5
358,884 + -0.3
358,885 - -0.4
358,955 - -0.4

Or see this region's nucleotide sequence