Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0016c

Experiment: heptadecanoic 250 uM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0015c and Rv0016c overlap by 4 nucleotidesRv0016c and Rv0017c overlap by 4 nucleotides Rv0015c: Rv0015c - Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A), at 17,467 to 18,762 Rv0015c Rv0016c: Rv0016c - Probable penicillin-binding protein PbpA, at 18,759 to 20,234 Rv0016c Rv0017c: Rv0017c - Probable cell division protein RodA, at 20,231 to 21,640 Rv0017c Position (kb) 18 19 20 21Strain fitness (log2 ratio) -1 0 1at 19.454 kb on - strand, within Rv0016cat 19.694 kb on - strand, within Rv0016cat 19.761 kb on - strand, within Rv0016cat 19.830 kb on - strand, within Rv0016cat 19.936 kb on - strand, within Rv0016cat 19.985 kb on - strand, within Rv0016cat 20.279 kb on - strandat 20.346 kb on - strandat 20.376 kb on + strand, within Rv0017cat 20.498 kb on - strand, within Rv0017cat 20.548 kb on - strand, within Rv0017cat 20.548 kb on - strand, within Rv0017cat 20.883 kb on + strand, within Rv0017cat 20.884 kb on - strand, within Rv0017c

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Per-strain Table

Position Strand Gene LocusTag Fraction heptadecanoic 250 uM (C)
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19,454 - Rv0016c 0.47 -0.8
19,694 - Rv0016c 0.63 -1.3
19,761 - Rv0016c 0.68 -0.4
19,830 - Rv0016c 0.73 -1.3
19,936 - Rv0016c 0.80 -1.0
19,985 - Rv0016c 0.83 -1.3
20,279 - +0.2
20,346 - -0.0
20,376 + Rv0017c 0.10 +0.5
20,498 - Rv0017c 0.19 -0.3
20,548 - Rv0017c 0.22 -1.0
20,548 - Rv0017c 0.22 -0.8
20,883 + Rv0017c 0.46 -0.8
20,884 - Rv0017c 0.46 -1.3

Or see this region's nucleotide sequence