Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1701

Experiment: butyrate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1699 and Rv1700 overlap by 8 nucleotidesRv1700 and Rv1701 overlap by 4 nucleotidesRv1701 and Rv1702c are separated by 73 nucleotides Rv1699: Rv1699 - Probable CTP synthase PyrG, at 1,923,829 to 1,925,589 Rv1699 Rv1700: Rv1700 - NUDIX hydrolase, at 1,925,582 to 1,926,205 Rv1700 Rv1701: Rv1701 - Probable integrase/recombinase, at 1,926,202 to 1,927,137 Rv1701 Rv1702c: Rv1702c - Conserved hypothetical protein, at 1,927,211 to 1,928,575 Rv1702c Position (kb) 1926 1927 1928Strain fitness (log2 ratio) -2 -1 0 1at 1925.763 kb on - strand, within Rv1700at 1926.664 kb on + strand, within Rv1701at 1926.665 kb on - strand, within Rv1701at 1926.970 kb on - strand, within Rv1701at 1926.970 kb on - strand, within Rv1701at 1927.073 kb on - strandat 1927.135 kb on + strandat 1927.261 kb on - strandat 1927.456 kb on - strand, within Rv1702cat 1927.463 kb on + strand, within Rv1702cat 1927.579 kb on + strand, within Rv1702cat 1927.580 kb on - strand, within Rv1702cat 1927.583 kb on + strand, within Rv1702cat 1927.583 kb on + strand, within Rv1702cat 1927.583 kb on + strand, within Rv1702cat 1927.583 kb on + strand, within Rv1702cat 1927.584 kb on - strand, within Rv1702cat 1927.584 kb on - strand, within Rv1702cat 1927.587 kb on + strand, within Rv1702cat 1927.587 kb on + strand, within Rv1702cat 1928.020 kb on - strand, within Rv1702cat 1928.060 kb on + strand, within Rv1702cat 1928.060 kb on + strand, within Rv1702cat 1928.060 kb on + strand, within Rv1702cat 1928.070 kb on - strand, within Rv1702cat 1928.070 kb on - strand, within Rv1702c

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Per-strain Table

Position Strand Gene LocusTag Fraction butyrate 10 mM (C)
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1,925,763 - Rv1700 0.29 -0.5
1,926,664 + Rv1701 0.49 -0.5
1,926,665 - Rv1701 0.49 -1.5
1,926,970 - Rv1701 0.82 -0.2
1,926,970 - Rv1701 0.82 -2.0
1,927,073 - +0.8
1,927,135 + -0.5
1,927,261 - -0.3
1,927,456 - Rv1702c 0.18 +0.8
1,927,463 + Rv1702c 0.18 +0.5
1,927,579 + Rv1702c 0.27 -0.8
1,927,580 - Rv1702c 0.27 -0.4
1,927,583 + Rv1702c 0.27 -0.3
1,927,583 + Rv1702c 0.27 -0.5
1,927,583 + Rv1702c 0.27 +0.6
1,927,583 + Rv1702c 0.27 +0.2
1,927,584 - Rv1702c 0.27 -0.4
1,927,584 - Rv1702c 0.27 +0.4
1,927,587 + Rv1702c 0.28 -0.8
1,927,587 + Rv1702c 0.28 -0.4
1,928,020 - Rv1702c 0.59 -1.0
1,928,060 + Rv1702c 0.62 +0.2
1,928,060 + Rv1702c 0.62 -0.6
1,928,060 + Rv1702c 0.62 -0.4
1,928,070 - Rv1702c 0.63 +0.4
1,928,070 - Rv1702c 0.63 +0.1

Or see this region's nucleotide sequence