Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1625c

Experiment: butyrate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1623c and Rv1624c are separated by 110 nucleotidesRv1624c and Rv1625c are separated by 28 nucleotidesRv1625c and GFF1690 are separated by 69 nucleotidesGFF1690 and Rv1626 are separated by 91 nucleotidesRv1626 and Rv1627c are separated by 67 nucleotides Rv1623c: Rv1623c - Probable integral membrane cytochrome D ubiquinol oxidase (subunit I) CydA (cytochrome BD-I oxidase subunit I), at 1,824,430 to 1,825,887 Rv1623c Rv1624c: Rv1624c - Probable conserved membrane protein, at 1,825,998 to 1,826,585 Rv1624c Rv1625c: Rv1625c - Membrane-anchored adenylyl cyclase Cya (ATP pyrophosphate-lyase) (adenylate cyclase), at 1,826,614 to 1,827,945 Rv1625c GFF1690 - tRNA-Leu, at 1,828,015 to 1,828,088 GFF1690 Rv1626: Rv1626 - Probable two-component system transcriptional regulator, at 1,828,180 to 1,828,797 Rv1626 Rv1627c: Rv1627c - Probable nonspecific lipid-transfer protein, at 1,828,865 to 1,830,073 Rv1627c Position (kb) 1826 1827 1828Strain fitness (log2 ratio) -1 0 1 2at 1825.940 kb on + strandat 1825.941 kb on - strandat 1825.943 kb on + strandat 1826.094 kb on + strand, within Rv1624cat 1826.094 kb on + strand, within Rv1624cat 1826.198 kb on + strand, within Rv1624cat 1826.198 kb on + strand, within Rv1624cat 1826.410 kb on + strand, within Rv1624cat 1826.410 kb on + strand, within Rv1624cat 1826.446 kb on - strand, within Rv1624cat 1826.587 kb on + strandat 1826.587 kb on + strandat 1826.587 kb on + strandat 1826.687 kb on + strandat 1826.688 kb on - strandat 1826.688 kb on - strandat 1826.688 kb on - strandat 1826.701 kb on + strandat 1826.701 kb on + strandat 1826.702 kb on - strandat 1826.722 kb on + strandat 1826.722 kb on + strandat 1826.722 kb on + strandat 1826.723 kb on - strandat 1826.723 kb on - strandat 1826.723 kb on - strandat 1826.723 kb on - strandat 1826.723 kb on - strandat 1826.723 kb on - strandat 1827.000 kb on + strand, within Rv1625cat 1827.042 kb on - strand, within Rv1625cat 1827.042 kb on - strand, within Rv1625cat 1827.042 kb on - strand, within Rv1625cat 1827.107 kb on + strand, within Rv1625cat 1827.108 kb on - strand, within Rv1625cat 1827.150 kb on + strand, within Rv1625cat 1827.207 kb on - strand, within Rv1625cat 1827.241 kb on - strand, within Rv1625cat 1827.241 kb on - strand, within Rv1625cat 1827.368 kb on - strand, within Rv1625cat 1827.404 kb on - strand, within Rv1625cat 1827.404 kb on - strand, within Rv1625cat 1827.550 kb on + strand, within Rv1625cat 1827.617 kb on + strand, within Rv1625cat 1827.636 kb on + strand, within Rv1625cat 1827.636 kb on + strand, within Rv1625cat 1827.637 kb on - strand, within Rv1625cat 1827.637 kb on - strand, within Rv1625cat 1827.637 kb on - strand, within Rv1625cat 1827.668 kb on - strand, within Rv1625cat 1827.668 kb on - strand, within Rv1625cat 1827.722 kb on + strand, within Rv1625cat 1827.722 kb on + strand, within Rv1625cat 1827.722 kb on + strand, within Rv1625cat 1827.722 kb on + strand, within Rv1625cat 1827.722 kb on + strand, within Rv1625cat 1827.722 kb on + strand, within Rv1625cat 1827.723 kb on - strand, within Rv1625cat 1827.723 kb on - strand, within Rv1625cat 1827.745 kb on + strand, within Rv1625cat 1827.746 kb on - strand, within Rv1625cat 1827.801 kb on + strand, within Rv1625cat 1827.801 kb on + strand, within Rv1625cat 1827.801 kb on + strand, within Rv1625cat 1827.801 kb on + strand, within Rv1625cat 1827.801 kb on + strand, within Rv1625cat 1827.802 kb on - strand, within Rv1625cat 1827.836 kb on + strandat 1827.914 kb on - strandat 1827.950 kb on + strandat 1827.950 kb on + strandat 1827.951 kb on - strandat 1827.951 kb on - strandat 1827.951 kb on - strandat 1827.970 kb on - strandat 1827.970 kb on - strandat 1828.292 kb on - strand, within Rv1626at 1828.432 kb on - strand, within Rv1626at 1828.510 kb on + strand, within Rv1626at 1828.511 kb on - strand, within Rv1626at 1828.517 kb on + strand, within Rv1626at 1828.613 kb on + strand, within Rv1626at 1828.866 kb on + strandat 1828.866 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction butyrate 10 mM (C)
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1,825,940 + +0.2
1,825,941 - +0.3
1,825,943 + -0.9
1,826,094 + Rv1624c 0.16 -0.6
1,826,094 + Rv1624c 0.16 +1.2
1,826,198 + Rv1624c 0.34 +0.6
1,826,198 + Rv1624c 0.34 -0.0
1,826,410 + Rv1624c 0.70 -0.1
1,826,410 + Rv1624c 0.70 -0.1
1,826,446 - Rv1624c 0.76 +0.2
1,826,587 + -0.4
1,826,587 + -0.4
1,826,587 + -0.0
1,826,687 + +0.8
1,826,688 - +0.8
1,826,688 - -0.5
1,826,688 - -1.2
1,826,701 + +0.0
1,826,701 + -1.0
1,826,702 - +0.6
1,826,722 + -0.2
1,826,722 + -0.4
1,826,722 + +0.2
1,826,723 - +0.1
1,826,723 - -0.6
1,826,723 - -0.3
1,826,723 - -0.0
1,826,723 - +1.3
1,826,723 - +0.5
1,827,000 + Rv1625c 0.29 -0.3
1,827,042 - Rv1625c 0.32 -0.6
1,827,042 - Rv1625c 0.32 +0.5
1,827,042 - Rv1625c 0.32 +1.5
1,827,107 + Rv1625c 0.37 -0.2
1,827,108 - Rv1625c 0.37 -0.3
1,827,150 + Rv1625c 0.40 +0.4
1,827,207 - Rv1625c 0.45 +1.3
1,827,241 - Rv1625c 0.47 -1.2
1,827,241 - Rv1625c 0.47 +0.1
1,827,368 - Rv1625c 0.57 -0.0
1,827,404 - Rv1625c 0.59 +0.9
1,827,404 - Rv1625c 0.59 -0.7
1,827,550 + Rv1625c 0.70 -0.0
1,827,617 + Rv1625c 0.75 -0.8
1,827,636 + Rv1625c 0.77 +1.5
1,827,636 + Rv1625c 0.77 +0.1
1,827,637 - Rv1625c 0.77 -0.1
1,827,637 - Rv1625c 0.77 +1.3
1,827,637 - Rv1625c 0.77 +0.8
1,827,668 - Rv1625c 0.79 -0.2
1,827,668 - Rv1625c 0.79 -1.3
1,827,722 + Rv1625c 0.83 +0.1
1,827,722 + Rv1625c 0.83 -0.8
1,827,722 + Rv1625c 0.83 +0.0
1,827,722 + Rv1625c 0.83 -0.1
1,827,722 + Rv1625c 0.83 -0.2
1,827,722 + Rv1625c 0.83 +0.5
1,827,723 - Rv1625c 0.83 +1.0
1,827,723 - Rv1625c 0.83 -0.1
1,827,745 + Rv1625c 0.85 +0.3
1,827,746 - Rv1625c 0.85 -1.5
1,827,801 + Rv1625c 0.89 -1.5
1,827,801 + Rv1625c 0.89 +0.1
1,827,801 + Rv1625c 0.89 +0.6
1,827,801 + Rv1625c 0.89 -0.2
1,827,801 + Rv1625c 0.89 -0.1
1,827,802 - Rv1625c 0.89 -0.5
1,827,836 + +0.1
1,827,914 - -0.1
1,827,950 + -0.6
1,827,950 + +0.0
1,827,951 - +0.1
1,827,951 - +0.1
1,827,951 - +0.0
1,827,970 - -0.1
1,827,970 - +0.4
1,828,292 - Rv1626 0.18 +0.8
1,828,432 - Rv1626 0.41 +0.8
1,828,510 + Rv1626 0.53 +0.0
1,828,511 - Rv1626 0.54 +0.3
1,828,517 + Rv1626 0.55 +0.1
1,828,613 + Rv1626 0.70 +0.5
1,828,866 + +1.8
1,828,866 + -0.6

Or see this region's nucleotide sequence