Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0399c

Experiment: butyrate 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0397A and Rv0398c are separated by 36 nucleotidesRv0398c and Rv0399c are separated by 6 nucleotidesRv0399c and Rv0400c are separated by 9 nucleotides Rv0397A: Rv0397A - Conserved protein, at 476,394 to 476,642 Rv0397A Rv0398c: Rv0398c - Possible secreted protein, at 476,679 to 477,320 Rv0398c Rv0399c: Rv0399c - Possible conserved lipoprotein LpqK, at 477,327 to 478,556 Rv0399c Rv0400c: Rv0400c - Acyl-CoA dehydrogenase FadE7, at 478,566 to 479,753 Rv0400c Position (kb) 477 478 479Strain fitness (log2 ratio) -2 -1 0 1 2 3at 476.345 kb on + strandat 476.426 kb on - strand, within Rv0397Aat 476.545 kb on + strand, within Rv0397Aat 476.546 kb on - strand, within Rv0397Aat 476.547 kb on + strand, within Rv0397Aat 476.547 kb on + strand, within Rv0397Aat 476.681 kb on - strandat 476.767 kb on + strand, within Rv0398cat 476.768 kb on - strand, within Rv0398cat 477.134 kb on + strand, within Rv0398cat 477.324 kb on + strandat 477.328 kb on + strandat 477.329 kb on - strandat 477.391 kb on - strandat 477.393 kb on + strandat 477.393 kb on + strandat 477.488 kb on - strand, within Rv0399cat 477.547 kb on - strand, within Rv0399cat 477.566 kb on - strand, within Rv0399cat 477.656 kb on - strand, within Rv0399cat 478.152 kb on + strand, within Rv0399cat 478.267 kb on + strand, within Rv0399cat 479.497 kb on + strand, within Rv0400cat 479.498 kb on - strand, within Rv0400cat 479.498 kb on - strand, within Rv0400cat 479.498 kb on - strand, within Rv0400c

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Per-strain Table

Position Strand Gene LocusTag Fraction butyrate 10 mM (C)
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476,345 + +0.5
476,426 - Rv0397A 0.13 +0.0
476,545 + Rv0397A 0.61 +0.2
476,546 - Rv0397A 0.61 -0.5
476,547 + Rv0397A 0.61 -0.4
476,547 + Rv0397A 0.61 +0.1
476,681 - -0.1
476,767 + Rv0398c 0.14 +0.1
476,768 - Rv0398c 0.14 -0.5
477,134 + Rv0398c 0.71 -0.7
477,324 + +0.0
477,328 + -0.3
477,329 - -0.1
477,391 - +0.2
477,393 + -0.1
477,393 + +3.7
477,488 - Rv0399c 0.13 +0.7
477,547 - Rv0399c 0.18 -2.5
477,566 - Rv0399c 0.19 -0.8
477,656 - Rv0399c 0.27 -1.1
478,152 + Rv0399c 0.67 +0.6
478,267 + Rv0399c 0.76 -1.1
479,497 + Rv0400c 0.78 +0.1
479,498 - Rv0400c 0.78 +1.6
479,498 - Rv0400c 0.78 -0.6
479,498 - Rv0400c 0.78 -0.4

Or see this region's nucleotide sequence