Experiment: butyrate 10 mM (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0155 and Rv0156 are separated by 0 nucleotides Rv0156 and Rv0157 overlap by 4 nucleotides Rv0157 and Rv0157A are separated by 15 nucleotides Rv0157A and Rv0158 are separated by 161 nucleotides Rv0158 and Rv0159c are separated by 3 nucleotides
Rv0155: Rv0155 - Probable NAD(P) transhydrogenase (subunit alpha) PntAa [first part; catalytic part] (pyridine nucleotide transhydrogenase subunit alpha) (nicotinamide nucleotide transhydrogenase subunit alpha), at 183,622 to 184,722
Rv0155
Rv0156: Rv0156 - Probable NAD(P) transhydrogenase (subunit alpha) PntAb [second part; integral membrane protein] (pyridine nucleotide transhydrogenase subunit alpha) (nicotinamide nucleotide transhydrogenase subunit alpha), at 184,723 to 185,055
Rv0156
Rv0157: Rv0157 - Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] (pyridine nucleotide transhydrogenase subunit beta) (nicotinamide nucleotide transhydrogenase subunit beta), at 185,052 to 186,479
Rv0157
Rv0157A: Rv0157A - Conserved protein, at 186,495 to 186,623
Rv0157A
Rv0158: Rv0158 - Probable transcriptional regulatory protein (possibly TetR-family), at 186,785 to 187,429
Rv0158
Rv0159c: Rv0159c - PE family protein PE3, at 187,433 to 188,839
Rv0159c
Position (kb) 185
186
187 Strain fitness (log2 ratio) -1
0
1
2 at 184.054 kb on - strand, within Rv0155 at 184.054 kb on - strand, within Rv0155 at 184.216 kb on + strand, within Rv0155 at 184.217 kb on - strand, within Rv0155 at 184.217 kb on - strand, within Rv0155 at 184.607 kb on - strand, within Rv0155 at 184.607 kb on - strand, within Rv0155 at 184.720 kb on + strand at 184.721 kb on - strand at 184.721 kb on - strand at 184.726 kb on + strand at 185.082 kb on + strand at 185.083 kb on - strand at 185.109 kb on + strand at 185.110 kb on - strand at 185.487 kb on - strand, within Rv0157 at 185.487 kb on - strand, within Rv0157 at 185.487 kb on - strand, within Rv0157 at 185.487 kb on - strand, within Rv0157 at 185.995 kb on - strand, within Rv0157 at 185.995 kb on - strand, within Rv0157 at 186.106 kb on - strand, within Rv0157 at 186.143 kb on + strand, within Rv0157 at 186.144 kb on - strand, within Rv0157 at 186.144 kb on - strand, within Rv0157 at 186.178 kb on - strand, within Rv0157 at 186.416 kb on + strand at 186.416 kb on + strand at 186.416 kb on + strand at 186.417 kb on - strand at 186.417 kb on - strand at 186.417 kb on - strand at 186.477 kb on + strand at 186.478 kb on - strand at 186.478 kb on - strand at 186.508 kb on + strand, within Rv0157A at 186.509 kb on - strand, within Rv0157A at 186.781 kb on - strand at 186.814 kb on - strand at 186.853 kb on - strand, within Rv0158 at 186.929 kb on + strand, within Rv0158 at 186.930 kb on - strand, within Rv0158 at 186.930 kb on - strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.936 kb on - strand, within Rv0158 at 186.971 kb on + strand, within Rv0158 at 187.043 kb on + strand, within Rv0158 at 187.103 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.122 kb on - strand, within Rv0158 at 187.185 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.235 kb on + strand, within Rv0158 at 187.269 kb on - strand, within Rv0158 at 187.292 kb on + strand, within Rv0158 at 187.292 kb on + strand, within Rv0158
Per-strain Table
Position Strand Gene LocusTag Fraction butyrate 10 mM (C) remove 184,054 - Rv0155 0.39 +2.1 184,054 - Rv0155 0.39 -0.9 184,216 + Rv0155 0.54 -0.0 184,217 - Rv0155 0.54 -0.2 184,217 - Rv0155 0.54 +0.1 184,607 - Rv0155 0.89 -0.8 184,607 - Rv0155 0.89 -0.3 184,720 + -0.0 184,721 - -0.6 184,721 - -0.8 184,726 + +0.6 185,082 + -0.1 185,083 - -0.4 185,109 + +0.2 185,110 - +1.3 185,487 - Rv0157 0.30 +0.9 185,487 - Rv0157 0.30 +0.3 185,487 - Rv0157 0.30 -0.5 185,487 - Rv0157 0.30 +1.2 185,995 - Rv0157 0.66 +0.8 185,995 - Rv0157 0.66 -0.1 186,106 - Rv0157 0.74 +0.3 186,143 + Rv0157 0.76 -0.3 186,144 - Rv0157 0.76 -0.1 186,144 - Rv0157 0.76 +2.1 186,178 - Rv0157 0.79 +0.6 186,416 + -1.2 186,416 + -1.2 186,416 + +1.4 186,417 - -0.9 186,417 - -1.0 186,417 - +0.1 186,477 + -0.8 186,478 - +0.4 186,478 - +0.1 186,508 + Rv0157A 0.10 +0.2 186,509 - Rv0157A 0.11 -0.0 186,781 - -0.6 186,814 - +0.1 186,853 - Rv0158 0.11 -0.9 186,929 + Rv0158 0.22 -0.5 186,930 - Rv0158 0.22 -0.8 186,930 - Rv0158 0.22 +0.8 186,935 + Rv0158 0.23 -0.7 186,935 + Rv0158 0.23 -0.6 186,935 + Rv0158 0.23 -0.7 186,935 + Rv0158 0.23 -0.9 186,936 - Rv0158 0.23 -0.3 186,971 + Rv0158 0.29 -0.6 187,043 + Rv0158 0.40 +0.2 187,103 + Rv0158 0.49 -0.4 187,121 + Rv0158 0.52 -0.3 187,121 + Rv0158 0.52 -1.0 187,121 + Rv0158 0.52 +0.4 187,122 - Rv0158 0.52 -0.5 187,185 - Rv0158 0.62 +0.3 187,195 - Rv0158 0.64 -1.1 187,195 - Rv0158 0.64 -1.0 187,195 - Rv0158 0.64 -0.5 187,235 + Rv0158 0.70 -0.7 187,269 - Rv0158 0.75 +1.1 187,292 + Rv0158 0.79 +0.5 187,292 + Rv0158 0.79 -1.0
Or see this region's nucleotide sequence