Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3134c

Experiment: Valeric 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3132c and Rv3133c overlap by 4 nucleotidesRv3133c and Rv3134c are separated by 27 nucleotidesRv3134c and Rv3135 are separated by 584 nucleotides Rv3132c: Rv3132c - Two component sensor histidine kinase DevS, at 3,497,529 to 3,499,265 Rv3132c Rv3133c: Rv3133c - Two component transcriptional regulatory protein DevR (probably LuxR/UhpA-family), at 3,499,262 to 3,499,915 Rv3133c Rv3134c: Rv3134c - Universal stress protein family protein, at 3,499,943 to 3,500,749 Rv3134c Rv3135: Rv3135 - PPE family protein PPE50, at 3,501,334 to 3,501,732 Rv3135 Position (kb) 3499 3500 3501Strain fitness (log2 ratio) -1 0 1at 3499.063 kb on - strand, within Rv3132cat 3499.365 kb on + strand, within Rv3133cat 3499.366 kb on - strand, within Rv3133cat 3499.644 kb on - strand, within Rv3133cat 3499.665 kb on + strand, within Rv3133cat 3499.666 kb on - strand, within Rv3133cat 3499.910 kb on + strandat 3499.944 kb on + strandat 3499.945 kb on - strandat 3499.967 kb on - strandat 3499.967 kb on - strandat 3499.970 kb on + strandat 3499.989 kb on + strandat 3499.989 kb on + strandat 3499.990 kb on - strandat 3500.153 kb on + strand, within Rv3134cat 3500.153 kb on + strand, within Rv3134cat 3500.154 kb on - strand, within Rv3134cat 3500.154 kb on - strand, within Rv3134cat 3500.625 kb on + strand, within Rv3134cat 3500.626 kb on - strand, within Rv3134cat 3500.626 kb on - strand, within Rv3134cat 3500.710 kb on + strandat 3500.774 kb on + strandat 3500.775 kb on - strandat 3500.801 kb on - strandat 3500.853 kb on + strandat 3500.909 kb on + strandat 3500.981 kb on - strandat 3501.196 kb on - strandat 3501.375 kb on + strand, within Rv3135at 3501.380 kb on - strand, within Rv3135at 3501.380 kb on - strand, within Rv3135at 3501.380 kb on - strand, within Rv3135at 3501.547 kb on + strand, within Rv3135at 3501.547 kb on + strand, within Rv3135at 3501.548 kb on - strand, within Rv3135

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Per-strain Table

Position Strand Gene LocusTag Fraction Valeric 10 mM (C)
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3,499,063 - Rv3132c 0.88 +0.2
3,499,365 + Rv3133c 0.16 +0.7
3,499,366 - Rv3133c 0.16 +1.0
3,499,644 - Rv3133c 0.58 +1.3
3,499,665 + Rv3133c 0.62 +1.4
3,499,666 - Rv3133c 0.62 +1.0
3,499,910 + +0.4
3,499,944 + +0.6
3,499,945 - -0.4
3,499,967 - -0.3
3,499,967 - -1.1
3,499,970 + +0.7
3,499,989 + +1.2
3,499,989 + +0.9
3,499,990 - -0.0
3,500,153 + Rv3134c 0.26 +0.6
3,500,153 + Rv3134c 0.26 +0.8
3,500,154 - Rv3134c 0.26 -0.2
3,500,154 - Rv3134c 0.26 -0.4
3,500,625 + Rv3134c 0.85 +1.1
3,500,626 - Rv3134c 0.85 +1.7
3,500,626 - Rv3134c 0.85 +0.2
3,500,710 + +0.9
3,500,774 + +0.4
3,500,775 - -0.5
3,500,801 - -0.7
3,500,853 + +0.0
3,500,909 + -0.3
3,500,981 - +1.0
3,501,196 - +0.7
3,501,375 + Rv3135 0.10 -1.0
3,501,380 - Rv3135 0.12 +0.3
3,501,380 - Rv3135 0.12 -0.9
3,501,380 - Rv3135 0.12 +1.0
3,501,547 + Rv3135 0.53 -0.7
3,501,547 + Rv3135 0.53 -0.3
3,501,548 - Rv3135 0.54 +0.4

Or see this region's nucleotide sequence