Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0992c

Experiment: Valeric 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0990c and Rv0991c are separated by 72 nucleotidesRv0991c and Rv0992c are separated by 73 nucleotidesRv0992c and Rv0993 are separated by 100 nucleotides Rv0990c: Rv0990c - Hypothetical protein, at 1,107,443 to 1,108,099 Rv0990c Rv0991c: Rv0991c - Conserved serine rich protein, at 1,108,172 to 1,108,504 Rv0991c Rv0992c: Rv0992c - Conserved hypothetical protein, at 1,108,578 to 1,109,171 Rv0992c Rv0993: Rv0993 - UTP--glucose-1-phosphate uridylyltransferase GalU (UDP-glucose pyrophosphorylase) (UDPGP) (alpha-D-glucosyl-1-phosphate uridylyltransferase) (uridine diphosphoglucose pyrophosphorylase), at 1,109,272 to 1,110,192 Rv0993 Position (kb) 1108 1109 1110Strain fitness (log2 ratio) -1 0 1at 1108.348 kb on - strand, within Rv0991cat 1108.488 kb on + strandat 1108.488 kb on + strandat 1108.495 kb on - strandat 1108.495 kb on - strandat 1108.638 kb on + strand, within Rv0992cat 1108.638 kb on + strand, within Rv0992cat 1108.639 kb on - strand, within Rv0992cat 1108.639 kb on - strand, within Rv0992cat 1108.639 kb on - strand, within Rv0992cat 1108.699 kb on - strand, within Rv0992cat 1108.738 kb on + strand, within Rv0992cat 1108.738 kb on + strand, within Rv0992cat 1108.739 kb on - strand, within Rv0992cat 1108.894 kb on + strand, within Rv0992cat 1108.895 kb on - strand, within Rv0992cat 1109.027 kb on - strand, within Rv0992cat 1109.027 kb on - strand, within Rv0992cat 1109.288 kb on + strandat 1109.291 kb on + strandat 1109.291 kb on + strandat 1109.291 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Valeric 10 mM (C)
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1,108,348 - Rv0991c 0.53 +0.1
1,108,488 + +0.0
1,108,488 + +0.6
1,108,495 - -0.1
1,108,495 - -0.6
1,108,638 + Rv0992c 0.10 -0.4
1,108,638 + Rv0992c 0.10 +0.3
1,108,639 - Rv0992c 0.10 -1.6
1,108,639 - Rv0992c 0.10 -0.9
1,108,639 - Rv0992c 0.10 +0.2
1,108,699 - Rv0992c 0.20 -0.1
1,108,738 + Rv0992c 0.27 -0.1
1,108,738 + Rv0992c 0.27 +0.2
1,108,739 - Rv0992c 0.27 +1.0
1,108,894 + Rv0992c 0.53 +0.3
1,108,895 - Rv0992c 0.53 -1.0
1,109,027 - Rv0992c 0.76 +1.3
1,109,027 - Rv0992c 0.76 -0.3
1,109,288 + -0.2
1,109,291 + -0.2
1,109,291 + -0.2
1,109,291 + -0.6

Or see this region's nucleotide sequence