Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0130

Experiment: Valeric 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0129c and Rv0130 are separated by 246 nucleotidesRv0130 and Rv0131c are separated by 12 nucleotides Rv0129c: Rv0129c - Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C), at 156,578 to 157,600 Rv0129c Rv0130: Rv0130 - Probable 3-hydroxyl-thioester dehydratase, at 157,847 to 158,302 Rv0130 Rv0131c: Rv0131c - Probable acyl-CoA dehydrogenase FadE1, at 158,315 to 159,658 Rv0131c Position (kb) 157 158 159Strain fitness (log2 ratio) -2 -1 0 1at 156.949 kb on - strand, within Rv0129cat 157.035 kb on + strand, within Rv0129cat 157.222 kb on - strand, within Rv0129cat 157.234 kb on - strand, within Rv0129cat 157.288 kb on - strand, within Rv0129cat 157.327 kb on - strand, within Rv0129cat 157.435 kb on - strand, within Rv0129cat 157.435 kb on - strand, within Rv0129cat 157.525 kb on + strandat 157.600 kb on + strandat 157.601 kb on - strandat 157.604 kb on + strandat 157.607 kb on + strandat 157.818 kb on - strandat 157.823 kb on + strandat 157.824 kb on - strandat 158.079 kb on - strand, within Rv0130at 158.638 kb on - strand, within Rv0131cat 158.761 kb on + strand, within Rv0131cat 158.840 kb on + strand, within Rv0131cat 159.045 kb on + strand, within Rv0131cat 159.046 kb on - strand, within Rv0131c

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Per-strain Table

Position Strand Gene LocusTag Fraction Valeric 10 mM (C)
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156,949 - Rv0129c 0.36 -2.4
157,035 + Rv0129c 0.45 -1.8
157,222 - Rv0129c 0.63 -0.3
157,234 - Rv0129c 0.64 -0.8
157,288 - Rv0129c 0.69 -1.6
157,327 - Rv0129c 0.73 -0.6
157,435 - Rv0129c 0.84 -0.8
157,435 - Rv0129c 0.84 +0.4
157,525 + -1.0
157,600 + -0.6
157,601 - -1.4
157,604 + -1.4
157,607 + +1.0
157,818 - -2.2
157,823 + -0.1
157,824 - -0.4
158,079 - Rv0130 0.51 +0.3
158,638 - Rv0131c 0.24 -0.7
158,761 + Rv0131c 0.33 +0.3
158,840 + Rv0131c 0.39 -1.1
159,045 + Rv0131c 0.54 +1.0
159,046 - Rv0131c 0.54 -0.4

Or see this region's nucleotide sequence