Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3386

Experiment: Valeric 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3384c and Rv3385c overlap by 1 nucleotidesRv3385c and Rv3386 are separated by 148 nucleotidesRv3386 and Rv3387 overlap by 11 nucleotidesRv3387 and Rv3388 are separated by 189 nucleotides Rv3384c: Rv3384c - Possible toxin VapC46. Contains PIN domain., at 3,799,243 to 3,799,635 Rv3384c Rv3385c: Rv3385c - Possible antitoxin VapB46, at 3,799,635 to 3,799,943 Rv3385c Rv3386: Rv3386 - Possible transposase, at 3,800,092 to 3,800,796 Rv3386 Rv3387: Rv3387 - Possible transposase, at 3,800,786 to 3,801,463 Rv3387 Rv3388: Rv3388 - PE-PGRS family protein PE_PGRS52, at 3,801,653 to 3,803,848 Rv3388 Position (kb) 3800 3801Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3799.121 kb on + strandat 3799.152 kb on - strandat 3799.155 kb on + strandat 3799.156 kb on - strandat 3799.156 kb on - strandat 3799.304 kb on + strand, within Rv3384cat 3799.622 kb on + strandat 3799.622 kb on + strandat 3799.623 kb on - strandat 3799.988 kb on - strandat 3800.105 kb on + strandat 3800.314 kb on + strand, within Rv3386at 3800.794 kb on + strandat 3801.356 kb on + strand, within Rv3387at 3801.356 kb on + strand, within Rv3387at 3801.546 kb on + strandat 3801.546 kb on + strandat 3801.546 kb on + strandat 3801.547 kb on - strandat 3801.547 kb on - strandat 3801.547 kb on - strandat 3801.549 kb on + strandat 3801.550 kb on + strandat 3801.550 kb on - strandat 3801.550 kb on - strandat 3801.550 kb on - strandat 3801.553 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Valeric 10 mM (C)
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3,799,121 + -0.1
3,799,152 - +0.3
3,799,155 + -0.1
3,799,156 - -0.0
3,799,156 - +0.5
3,799,304 + Rv3384c 0.16 +3.3
3,799,622 + -0.2
3,799,622 + +1.2
3,799,623 - +3.2
3,799,988 - -0.8
3,800,105 + +1.7
3,800,314 + Rv3386 0.31 +0.5
3,800,794 + +1.0
3,801,356 + Rv3387 0.84 +0.6
3,801,356 + Rv3387 0.84 +0.2
3,801,546 + -1.9
3,801,546 + -0.5
3,801,546 + -1.3
3,801,547 - -0.6
3,801,547 - -0.7
3,801,547 - -0.7
3,801,549 + -0.0
3,801,550 + +0.3
3,801,550 - +0.2
3,801,550 - -0.8
3,801,550 - -0.4
3,801,553 + +0.2

Or see this region's nucleotide sequence