Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1948c

Experiment: Valeric 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1946c and Rv1947 are separated by 63 nucleotidesRv1947 and Rv1948c are separated by 288 nucleotidesRv1948c and Rv1949c are separated by 10 nucleotidesRv1949c and Rv1950c overlap by 37 nucleotides Rv1946c: Rv1946c - Possible lipoprotein, at 2,197,508 to 2,197,960 Rv1946c Rv1947: Rv1947 - Hypothetical protein, at 2,198,024 to 2,198,425 Rv1947 Rv1948c: Rv1948c - Hypothetical protein, at 2,198,714 to 2,199,064 Rv1948c Rv1949c: Rv1949c - Conserved hypothetical protein, at 2,199,075 to 2,200,034 Rv1949c Rv1950c: Rv1950c - Conserved hypothetical protein, at 2,199,998 to 2,200,189 Rv1950c Position (kb) 2198 2199 2200Strain fitness (log2 ratio) -2 -1 0 1at 2197.847 kb on + strand, within Rv1946cat 2197.847 kb on + strand, within Rv1946cat 2198.243 kb on + strand, within Rv1947at 2198.420 kb on - strandat 2198.451 kb on + strandat 2198.604 kb on - strandat 2198.922 kb on - strand, within Rv1948cat 2198.930 kb on + strand, within Rv1948cat 2198.930 kb on + strand, within Rv1948cat 2198.931 kb on - strand, within Rv1948cat 2198.977 kb on - strand, within Rv1948cat 2199.033 kb on + strandat 2199.034 kb on - strandat 2199.167 kb on - strandat 2199.267 kb on + strand, within Rv1949cat 2199.306 kb on + strand, within Rv1949cat 2199.306 kb on + strand, within Rv1949cat 2199.306 kb on + strand, within Rv1949cat 2199.307 kb on - strand, within Rv1949cat 2199.499 kb on + strand, within Rv1949cat 2199.499 kb on + strand, within Rv1949cat 2199.546 kb on + strand, within Rv1949cat 2199.547 kb on - strand, within Rv1949cat 2199.547 kb on - strand, within Rv1949cat 2199.698 kb on + strand, within Rv1949cat 2199.698 kb on + strand, within Rv1949cat 2199.721 kb on - strand, within Rv1949cat 2199.907 kb on + strand, within Rv1949cat 2199.907 kb on + strand, within Rv1949cat 2199.908 kb on - strand, within Rv1949cat 2199.908 kb on - strand, within Rv1949cat 2199.999 kb on + strandat 2200.000 kb on - strandat 2200.000 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Valeric 10 mM (C)
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2,197,847 + Rv1946c 0.75 +0.9
2,197,847 + Rv1946c 0.75 -2.2
2,198,243 + Rv1947 0.54 -1.6
2,198,420 - -0.5
2,198,451 + +0.7
2,198,604 - -1.1
2,198,922 - Rv1948c 0.59 -1.2
2,198,930 + Rv1948c 0.62 +0.4
2,198,930 + Rv1948c 0.62 +0.5
2,198,931 - Rv1948c 0.62 -0.1
2,198,977 - Rv1948c 0.75 +0.5
2,199,033 + -0.4
2,199,034 - -0.3
2,199,167 - -0.1
2,199,267 + Rv1949c 0.20 -0.9
2,199,306 + Rv1949c 0.24 -0.3
2,199,306 + Rv1949c 0.24 -2.2
2,199,306 + Rv1949c 0.24 -0.8
2,199,307 - Rv1949c 0.24 -0.4
2,199,499 + Rv1949c 0.44 -0.2
2,199,499 + Rv1949c 0.44 -0.3
2,199,546 + Rv1949c 0.49 -0.4
2,199,547 - Rv1949c 0.49 -0.2
2,199,547 - Rv1949c 0.49 +0.4
2,199,698 + Rv1949c 0.65 -0.2
2,199,698 + Rv1949c 0.65 +0.1
2,199,721 - Rv1949c 0.67 -0.7
2,199,907 + Rv1949c 0.87 -0.5
2,199,907 + Rv1949c 0.87 -0.0
2,199,908 - Rv1949c 0.87 +0.0
2,199,908 - Rv1949c 0.87 +1.5
2,199,999 + +0.2
2,200,000 - -0.2
2,200,000 - -0.4

Or see this region's nucleotide sequence