Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1345

Experiment: Valeric 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1342c and Rv1343c overlap by 4 nucleotidesRv1343c and Rv1344 are separated by 44 nucleotidesRv1344 and Rv1345 overlap by 8 nucleotidesRv1345 and Rv1346 overlap by 1 nucleotides Rv1342c: Rv1342c - Conserved membrane protein, at 1,508,184 to 1,508,546 Rv1342c Rv1343c: Rv1343c - Probable conserved lipoprotein LprD, at 1,508,543 to 1,508,923 Rv1343c Rv1344: Rv1344 - Acyl carrier protein (ACP) MbtL, at 1,508,968 to 1,509,288 Rv1344 Rv1345: Rv1345 - Probable fatty acyl-AMP ligase MbtM, at 1,509,281 to 1,510,846 Rv1345 Rv1346: Rv1346 - Acyl-CoA dehydrogenase MbtN, at 1,510,846 to 1,512,006 Rv1346 Position (kb) 1509 1510 1511Strain fitness (log2 ratio) -1 0 1 2 3at 1508.586 kb on - strand, within Rv1343cat 1508.985 kb on - strandat 1509.020 kb on + strand, within Rv1344at 1509.021 kb on - strand, within Rv1344at 1509.021 kb on - strand, within Rv1344at 1509.063 kb on + strand, within Rv1344at 1509.391 kb on - strandat 1509.426 kb on + strandat 1509.544 kb on - strand, within Rv1345at 1509.616 kb on - strand, within Rv1345at 1509.616 kb on - strand, within Rv1345at 1509.632 kb on + strand, within Rv1345at 1509.633 kb on - strand, within Rv1345at 1509.659 kb on - strand, within Rv1345at 1509.880 kb on - strand, within Rv1345at 1510.061 kb on + strand, within Rv1345at 1510.062 kb on - strand, within Rv1345at 1510.205 kb on + strand, within Rv1345at 1510.297 kb on + strand, within Rv1345at 1510.338 kb on + strand, within Rv1345at 1510.339 kb on - strand, within Rv1345at 1510.991 kb on + strand, within Rv1346at 1511.146 kb on + strand, within Rv1346at 1511.252 kb on + strand, within Rv1346at 1511.253 kb on - strand, within Rv1346at 1511.368 kb on - strand, within Rv1346at 1511.682 kb on + strand, within Rv1346

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Per-strain Table

Position Strand Gene LocusTag Fraction Valeric 10 mM (C)
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1,508,586 - Rv1343c 0.11 -0.5
1,508,985 - -1.0
1,509,020 + Rv1344 0.16 -1.0
1,509,021 - Rv1344 0.17 -0.3
1,509,021 - Rv1344 0.17 -0.8
1,509,063 + Rv1344 0.30 +0.7
1,509,391 - -0.4
1,509,426 + -0.7
1,509,544 - Rv1345 0.17 +0.3
1,509,616 - Rv1345 0.21 -0.7
1,509,616 - Rv1345 0.21 +0.4
1,509,632 + Rv1345 0.22 -1.4
1,509,633 - Rv1345 0.22 -0.2
1,509,659 - Rv1345 0.24 -0.6
1,509,880 - Rv1345 0.38 -0.6
1,510,061 + Rv1345 0.50 -0.7
1,510,062 - Rv1345 0.50 -0.7
1,510,205 + Rv1345 0.59 -0.2
1,510,297 + Rv1345 0.65 +0.1
1,510,338 + Rv1345 0.67 -0.5
1,510,339 - Rv1345 0.68 -0.9
1,510,991 + Rv1346 0.12 -0.6
1,511,146 + Rv1346 0.26 +2.9
1,511,252 + Rv1346 0.35 -0.5
1,511,253 - Rv1346 0.35 -0.4
1,511,368 - Rv1346 0.45 +0.1
1,511,682 + Rv1346 0.72 -0.7

Or see this region's nucleotide sequence