Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3119

Experiment: casaminos 1 mg/mL (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3117 and Rv3118 are separated by 1 nucleotidesRv3118 and Rv3119 are separated by 20 nucleotidesRv3119 and Rv3120 overlap by 4 nucleotidesRv3120 and Rv3121 are separated by 334 nucleotides Rv3117: Rv3117 - Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase), at 3,483,974 to 3,484,807 Rv3117 Rv3118: Rv3118 - Conserved hypothetical protein SseC1, at 3,484,809 to 3,485,111 Rv3118 Rv3119: Rv3119 - Probable molybdenum cofactor biosynthesis protein E MoaE1 (molybdopterin converting factor large subunit) (molybdopterin [MPT] converting factor, subunit 2), at 3,485,132 to 3,485,575 Rv3119 Rv3120: Rv3120 - Conserved hypothetical protein, at 3,485,572 to 3,486,174 Rv3120 Rv3121: Rv3121 - Probable cytochrome P450 141 Cyp141, at 3,486,509 to 3,487,711 Rv3121 Position (kb) 3485 3486Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 3485.092 kb on + strandat 3485.112 kb on + strandat 3485.112 kb on + strandat 3485.116 kb on + strandat 3485.116 kb on + strandat 3485.116 kb on + strandat 3485.116 kb on + strandat 3485.117 kb on - strandat 3485.145 kb on + strandat 3485.146 kb on - strandat 3485.165 kb on + strandat 3485.303 kb on + strand, within Rv3119at 3485.485 kb on + strand, within Rv3119at 3485.486 kb on - strand, within Rv3119at 3485.566 kb on + strandat 3485.675 kb on + strand, within Rv3120at 3485.925 kb on - strand, within Rv3120at 3485.937 kb on - strand, within Rv3120at 3485.937 kb on - strand, within Rv3120at 3485.993 kb on + strand, within Rv3120at 3485.994 kb on - strand, within Rv3120at 3486.189 kb on + strandat 3486.189 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction casaminos 1 mg/mL (C)
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3,485,092 + -0.0
3,485,112 + -1.6
3,485,112 + +2.3
3,485,116 + +0.9
3,485,116 + -1.9
3,485,116 + -2.9
3,485,116 + -1.7
3,485,117 - +0.1
3,485,145 + -0.1
3,485,146 - +0.5
3,485,165 + +0.9
3,485,303 + Rv3119 0.39 +0.7
3,485,485 + Rv3119 0.80 -0.1
3,485,486 - Rv3119 0.80 +0.1
3,485,566 + -1.1
3,485,675 + Rv3120 0.17 +0.7
3,485,925 - Rv3120 0.59 -0.6
3,485,937 - Rv3120 0.61 +0.7
3,485,937 - Rv3120 0.61 +0.0
3,485,993 + Rv3120 0.70 -0.4
3,485,994 - Rv3120 0.70 -0.2
3,486,189 + -0.5
3,486,189 + +1.1

Or see this region's nucleotide sequence