Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1425

Experiment: casaminos 1 mg/mL (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1423 and Rv1424c are separated by 9 nucleotidesRv1424c and Rv1425 are separated by 3 nucleotidesRv1425 and Rv1426c are separated by 21 nucleotides Rv1423: Rv1423 - Probable transcriptional regulatory protein WhiA, at 1,597,906 to 1,598,883 Rv1423 Rv1424c: Rv1424c - Possible membrane protein, at 1,598,893 to 1,599,654 Rv1424c Rv1425: Rv1425 - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 1,599,658 to 1,601,037 Rv1425 Rv1426c: Rv1426c - Probable esterase LipO, at 1,601,059 to 1,602,321 Rv1426c Position (kb) 1599 1600 1601 1602Strain fitness (log2 ratio) -2 -1 0 1at 1598.895 kb on - strandat 1599.179 kb on + strand, within Rv1424cat 1599.210 kb on - strand, within Rv1424cat 1599.213 kb on - strand, within Rv1424cat 1599.213 kb on - strand, within Rv1424cat 1599.356 kb on + strand, within Rv1424cat 1599.357 kb on - strand, within Rv1424cat 1599.423 kb on - strand, within Rv1424cat 1599.440 kb on + strand, within Rv1424cat 1599.550 kb on - strand, within Rv1424cat 1599.646 kb on + strandat 1599.655 kb on - strandat 1599.655 kb on - strandat 1599.655 kb on - strandat 1599.717 kb on + strandat 1599.717 kb on + strandat 1599.718 kb on - strandat 1599.767 kb on - strandat 1599.767 kb on - strandat 1599.980 kb on - strand, within Rv1425at 1599.980 kb on - strand, within Rv1425at 1600.481 kb on - strand, within Rv1425at 1600.481 kb on - strand, within Rv1425at 1600.612 kb on - strand, within Rv1425at 1600.757 kb on - strand, within Rv1425at 1600.837 kb on + strand, within Rv1425at 1600.837 kb on + strand, within Rv1425at 1600.837 kb on + strand, within Rv1425at 1600.837 kb on + strand, within Rv1425at 1600.838 kb on - strand, within Rv1425at 1600.838 kb on - strand, within Rv1425at 1600.838 kb on - strand, within Rv1425at 1600.838 kb on - strand, within Rv1425at 1600.839 kb on + strand, within Rv1425at 1600.839 kb on + strand, within Rv1425at 1600.839 kb on + strand, within Rv1425at 1600.840 kb on - strand, within Rv1425at 1600.930 kb on + strandat 1601.035 kb on + strandat 1601.041 kb on + strandat 1601.041 kb on + strandat 1601.041 kb on + strandat 1601.051 kb on - strandat 1601.052 kb on + strandat 1601.053 kb on - strandat 1601.060 kb on + strandat 1601.084 kb on + strandat 1601.672 kb on + strand, within Rv1426cat 1601.673 kb on - strand, within Rv1426cat 1601.673 kb on - strand, within Rv1426cat 1601.858 kb on + strand, within Rv1426cat 1601.858 kb on + strand, within Rv1426cat 1601.934 kb on + strand, within Rv1426cat 1601.970 kb on + strand, within Rv1426cat 1601.975 kb on + strand, within Rv1426c

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Per-strain Table

Position Strand Gene LocusTag Fraction casaminos 1 mg/mL (C)
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1,598,895 - -0.5
1,599,179 + Rv1424c 0.38 -0.7
1,599,210 - Rv1424c 0.42 +1.1
1,599,213 - Rv1424c 0.42 -0.3
1,599,213 - Rv1424c 0.42 +1.2
1,599,356 + Rv1424c 0.61 +0.2
1,599,357 - Rv1424c 0.61 +0.3
1,599,423 - Rv1424c 0.70 -0.2
1,599,440 + Rv1424c 0.72 -0.1
1,599,550 - Rv1424c 0.86 -0.3
1,599,646 + -1.3
1,599,655 - -0.7
1,599,655 - -0.5
1,599,655 - +0.8
1,599,717 + -0.0
1,599,717 + -0.9
1,599,718 - -0.3
1,599,767 - +0.5
1,599,767 - -0.1
1,599,980 - Rv1425 0.23 -2.2
1,599,980 - Rv1425 0.23 +0.0
1,600,481 - Rv1425 0.60 -0.2
1,600,481 - Rv1425 0.60 -1.9
1,600,612 - Rv1425 0.69 +0.4
1,600,757 - Rv1425 0.80 +0.5
1,600,837 + Rv1425 0.85 +0.0
1,600,837 + Rv1425 0.85 -0.8
1,600,837 + Rv1425 0.85 -0.6
1,600,837 + Rv1425 0.85 +0.7
1,600,838 - Rv1425 0.86 -0.4
1,600,838 - Rv1425 0.86 +0.0
1,600,838 - Rv1425 0.86 -0.1
1,600,838 - Rv1425 0.86 -0.2
1,600,839 + Rv1425 0.86 -0.2
1,600,839 + Rv1425 0.86 -0.1
1,600,839 + Rv1425 0.86 -0.3
1,600,840 - Rv1425 0.86 -0.3
1,600,930 + -0.3
1,601,035 + +0.7
1,601,041 + +0.3
1,601,041 + -0.2
1,601,041 + -0.5
1,601,051 - -0.3
1,601,052 + +0.0
1,601,053 - +0.5
1,601,060 + -0.7
1,601,084 + +0.2
1,601,672 + Rv1426c 0.49 +0.4
1,601,673 - Rv1426c 0.49 +0.2
1,601,673 - Rv1426c 0.49 +0.6
1,601,858 + Rv1426c 0.63 -0.3
1,601,858 + Rv1426c 0.63 +1.4
1,601,934 + Rv1426c 0.69 +0.1
1,601,970 + Rv1426c 0.72 +0.0
1,601,975 + Rv1426c 0.73 -0.2

Or see this region's nucleotide sequence