Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1182

Experiment: casaminos 1 mg/mL (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1181 and Rv1182 are separated by 52 nucleotidesRv1182 and Rv1183 are separated by 66 nucleotides Rv1181: Rv1181 - Probable polyketide beta-ketoacyl synthase Pks4, at 1,315,234 to 1,319,982 Rv1181 Rv1182: Rv1182 - Probable conserved polyketide synthase associated protein PapA3, at 1,320,035 to 1,321,453 Rv1182 Rv1183: Rv1183 - Probable conserved transmembrane transport protein MmpL10, at 1,321,520 to 1,324,528 Rv1183 Position (kb) 1320 1321 1322Strain fitness (log2 ratio) -1 0 1at 1319.238 kb on + strand, within Rv1181at 1319.399 kb on - strand, within Rv1181at 1319.830 kb on + strandat 1320.191 kb on - strand, within Rv1182at 1320.200 kb on + strand, within Rv1182at 1320.325 kb on + strand, within Rv1182at 1320.326 kb on - strand, within Rv1182at 1320.347 kb on + strand, within Rv1182at 1320.366 kb on + strand, within Rv1182at 1320.367 kb on - strand, within Rv1182at 1320.367 kb on - strand, within Rv1182at 1320.606 kb on - strand, within Rv1182at 1320.751 kb on + strand, within Rv1182at 1320.907 kb on - strand, within Rv1182at 1321.162 kb on - strand, within Rv1182at 1321.268 kb on + strand, within Rv1182at 1321.290 kb on - strand, within Rv1182at 1321.304 kb on + strand, within Rv1182at 1321.305 kb on - strand, within Rv1182at 1321.305 kb on - strand, within Rv1182at 1321.693 kb on - strandat 1321.810 kb on + strandat 1321.838 kb on - strand, within Rv1183at 1321.840 kb on + strand, within Rv1183at 1321.892 kb on - strand, within Rv1183at 1321.914 kb on - strand, within Rv1183at 1322.280 kb on - strand, within Rv1183

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Per-strain Table

Position Strand Gene LocusTag Fraction casaminos 1 mg/mL (C)
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1,319,238 + Rv1181 0.84 -0.1
1,319,399 - Rv1181 0.88 +1.3
1,319,830 + +0.7
1,320,191 - Rv1182 0.11 -0.2
1,320,200 + Rv1182 0.12 +0.0
1,320,325 + Rv1182 0.20 +0.2
1,320,326 - Rv1182 0.21 +1.0
1,320,347 + Rv1182 0.22 +0.1
1,320,366 + Rv1182 0.23 +0.1
1,320,367 - Rv1182 0.23 +0.1
1,320,367 - Rv1182 0.23 +0.6
1,320,606 - Rv1182 0.40 +0.7
1,320,751 + Rv1182 0.50 +1.5
1,320,907 - Rv1182 0.61 -1.0
1,321,162 - Rv1182 0.79 -0.0
1,321,268 + Rv1182 0.87 +0.5
1,321,290 - Rv1182 0.88 -1.0
1,321,304 + Rv1182 0.89 +0.6
1,321,305 - Rv1182 0.89 +0.6
1,321,305 - Rv1182 0.89 +0.3
1,321,693 - -0.6
1,321,810 + +0.6
1,321,838 - Rv1183 0.11 -0.2
1,321,840 + Rv1183 0.11 -0.8
1,321,892 - Rv1183 0.12 -0.2
1,321,914 - Rv1183 0.13 -0.6
1,322,280 - Rv1183 0.25 +0.2

Or see this region's nucleotide sequence