Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3448

Experiment: D-Trehalose 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3447c and Rv3448 are separated by 113 nucleotidesRv3448 and Rv3449 overlap by 4 nucleotides Rv3447c: Rv3447c - ESX conserved component EccC4. ESX-4 type VII secretion system protein. Probable membrane protein., at 3,864,528 to 3,868,238 Rv3447c Rv3448: Rv3448 - ESX conserved component EccD4. ESX-4 type VII secretion system protein. Probable integral membrane protein., at 3,868,352 to 3,869,755 Rv3448 Rv3449: Rv3449 - Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4), at 3,869,752 to 3,871,119 Rv3449 Position (kb) 3868 3869 3870Strain fitness (log2 ratio) -2 -1 0 1at 3867.895 kb on - strandat 3867.955 kb on + strandat 3867.956 kb on - strandat 3868.251 kb on + strandat 3868.252 kb on - strandat 3868.297 kb on - strandat 3868.340 kb on + strandat 3868.357 kb on + strandat 3868.357 kb on + strandat 3868.390 kb on - strandat 3868.603 kb on + strand, within Rv3448at 3868.875 kb on - strand, within Rv3448at 3869.170 kb on - strand, within Rv3448at 3869.442 kb on + strand, within Rv3448at 3869.518 kb on + strand, within Rv3448at 3869.519 kb on - strand, within Rv3448at 3869.787 kb on - strandat 3869.918 kb on + strand, within Rv3449at 3869.918 kb on + strand, within Rv3449at 3869.919 kb on - strand, within Rv3449at 3870.098 kb on - strand, within Rv3449at 3870.098 kb on - strand, within Rv3449at 3870.098 kb on - strand, within Rv3449at 3870.159 kb on + strand, within Rv3449at 3870.159 kb on + strand, within Rv3449at 3870.210 kb on + strand, within Rv3449at 3870.404 kb on + strand, within Rv3449at 3870.404 kb on + strand, within Rv3449at 3870.468 kb on + strand, within Rv3449at 3870.551 kb on - strand, within Rv3449at 3870.559 kb on + strand, within Rv3449at 3870.573 kb on - strand, within Rv3449at 3870.573 kb on - strand, within Rv3449at 3870.573 kb on - strand, within Rv3449

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Trehalose 10 mM (C)
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3,867,895 - +0.5
3,867,955 + +0.1
3,867,956 - -0.6
3,868,251 + -1.4
3,868,252 - -0.0
3,868,297 - +0.2
3,868,340 + +0.1
3,868,357 + -0.1
3,868,357 + -0.2
3,868,390 - -0.4
3,868,603 + Rv3448 0.18 -0.4
3,868,875 - Rv3448 0.37 -0.5
3,869,170 - Rv3448 0.58 -0.5
3,869,442 + Rv3448 0.78 -1.1
3,869,518 + Rv3448 0.83 -2.2
3,869,519 - Rv3448 0.83 -0.7
3,869,787 - +0.2
3,869,918 + Rv3449 0.12 -2.3
3,869,918 + Rv3449 0.12 -0.3
3,869,919 - Rv3449 0.12 -0.8
3,870,098 - Rv3449 0.25 -0.3
3,870,098 - Rv3449 0.25 -0.1
3,870,098 - Rv3449 0.25 +0.6
3,870,159 + Rv3449 0.30 +1.1
3,870,159 + Rv3449 0.30 +0.5
3,870,210 + Rv3449 0.33 -0.2
3,870,404 + Rv3449 0.48 +0.5
3,870,404 + Rv3449 0.48 -0.6
3,870,468 + Rv3449 0.52 +0.6
3,870,551 - Rv3449 0.58 +0.1
3,870,559 + Rv3449 0.59 -0.9
3,870,573 - Rv3449 0.60 -0.2
3,870,573 - Rv3449 0.60 -0.1
3,870,573 - Rv3449 0.60 -0.0

Or see this region's nucleotide sequence