Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3003c

Experiment: D-Trehalose 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3001c and Rv3002c are separated by 37 nucleotidesRv3002c and Rv3003c overlap by 1 nucleotidesRv3003c and Rv3004 are separated by 361 nucleotidesRv3004 and Rv3005c are separated by 6 nucleotides Rv3001c: Rv3001c - Probable KETOL-acid reductoisomerase IlvC (acetohydroxy-acid isomeroreductase) (alpha-keto-beta-hydroxylacil reductoisomerase), at 3,359,585 to 3,360,586 Rv3001c Rv3002c: Rv3002c - Probable acetolactate synthase (small subunit) IlvN (acetohydroxy-acid synthase) (AHAS) (ALS), at 3,360,624 to 3,361,130 Rv3002c Rv3003c: Rv3003c - Acetolactate synthase (large subunit) IlvB1 (acetohydroxy-acid synthase), at 3,361,130 to 3,362,986 Rv3003c Rv3004: Rv3004 - Low molecular weight protein antigen 6 (CFP-6), at 3,363,348 to 3,363,686 Rv3004 Rv3005c: Rv3005c - Conserved hypothetical protein, at 3,363,693 to 3,364,532 Rv3005c Position (kb) 3361 3362 3363Strain fitness (log2 ratio) -2 -1 0 1at 3360.622 kb on - strandat 3363.091 kb on - strandat 3363.118 kb on - strandat 3363.118 kb on - strandat 3363.153 kb on - strandat 3363.166 kb on - strandat 3363.398 kb on - strand, within Rv3004at 3363.427 kb on + strand, within Rv3004at 3363.766 kb on - strandat 3363.780 kb on - strand, within Rv3005cat 3363.780 kb on - strand, within Rv3005cat 3363.878 kb on - strand, within Rv3005cat 3363.878 kb on - strand, within Rv3005cat 3363.901 kb on + strand, within Rv3005cat 3363.901 kb on + strand, within Rv3005cat 3363.901 kb on + strand, within Rv3005c

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Trehalose 10 mM (C)
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3,360,622 - -0.5
3,363,091 - -0.3
3,363,118 - -1.8
3,363,118 - -0.3
3,363,153 - -0.5
3,363,166 - -1.3
3,363,398 - Rv3004 0.15 +0.3
3,363,427 + Rv3004 0.23 -1.5
3,363,766 - +0.2
3,363,780 - Rv3005c 0.10 -0.3
3,363,780 - Rv3005c 0.10 +0.6
3,363,878 - Rv3005c 0.22 +0.2
3,363,878 - Rv3005c 0.22 -0.4
3,363,901 + Rv3005c 0.25 -1.3
3,363,901 + Rv3005c 0.25 -1.1
3,363,901 + Rv3005c 0.25 +0.6

Or see this region's nucleotide sequence