Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2494

Experiment: D-Trehalose 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2492 and Rv2493 are separated by 52 nucleotidesRv2493 and Rv2494 are separated by 5 nucleotidesRv2494 and Rv2495c are separated by 22 nucleotides Rv2492: Rv2492 - Hypothetical protein, at 2,807,278 to 2,808,030 Rv2492 Rv2493: Rv2493 - Possible antitoxin VapB38, at 2,808,083 to 2,808,304 Rv2493 Rv2494: Rv2494 - Possible toxin VapC38. Contains PIN domain., at 2,808,310 to 2,808,735 Rv2494 Rv2495c: Rv2495c - Probable branched-chain keto acid dehydrogenase E2 component BkdC, at 2,808,758 to 2,809,939 Rv2495c Position (kb) 2808 2809Strain fitness (log2 ratio) -2 -1 0 1at 2807.331 kb on - strandat 2807.409 kb on - strand, within Rv2492at 2807.492 kb on + strand, within Rv2492at 2807.944 kb on - strand, within Rv2492at 2808.029 kb on - strandat 2808.040 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Trehalose 10 mM (C)
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2,807,331 - -1.8
2,807,409 - Rv2492 0.17 +1.3
2,807,492 + Rv2492 0.28 -0.1
2,807,944 - Rv2492 0.88 +0.2
2,808,029 - +0.3
2,808,040 + +1.1

Or see this region's nucleotide sequence