Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1249c

Experiment: D-Trehalose 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1248c and Rv1249c are separated by 141 nucleotidesRv1249c and Rv1250 are separated by 196 nucleotides Rv1248c: Rv1248c - Multifunctional alpha-ketoglutarate metabolic enzyme, at 1,389,357 to 1,393,052 Rv1248c Rv1249c: Rv1249c - Possible membrane protein, at 1,393,194 to 1,393,982 Rv1249c Rv1250: Rv1250 - Probable drug-transport integral membrane protein, at 1,394,179 to 1,395,918 Rv1250 Position (kb) 1393 1394Strain fitness (log2 ratio) -1 0 1 2at 1393.218 kb on + strandat 1393.219 kb on - strandat 1393.400 kb on - strand, within Rv1249cat 1393.400 kb on - strand, within Rv1249cat 1393.400 kb on - strand, within Rv1249cat 1393.400 kb on - strand, within Rv1249cat 1393.514 kb on + strand, within Rv1249cat 1393.587 kb on + strand, within Rv1249cat 1393.687 kb on - strand, within Rv1249cat 1393.705 kb on - strand, within Rv1249cat 1393.705 kb on - strand, within Rv1249cat 1393.705 kb on - strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.810 kb on + strand, within Rv1249cat 1393.811 kb on - strand, within Rv1249cat 1393.811 kb on - strand, within Rv1249cat 1394.079 kb on + strandat 1394.178 kb on + strandat 1394.179 kb on - strandat 1394.179 kb on - strandat 1394.179 kb on - strandat 1394.185 kb on - strandat 1394.216 kb on - strandat 1394.292 kb on - strandat 1394.325 kb on - strandat 1394.365 kb on + strand, within Rv1250at 1394.377 kb on + strand, within Rv1250at 1394.551 kb on - strand, within Rv1250at 1394.769 kb on - strand, within Rv1250at 1394.847 kb on - strand, within Rv1250

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Trehalose 10 mM (C)
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1,393,218 + +1.1
1,393,219 - +0.0
1,393,400 - Rv1249c 0.26 +0.3
1,393,400 - Rv1249c 0.26 -0.5
1,393,400 - Rv1249c 0.26 +0.1
1,393,400 - Rv1249c 0.26 +1.6
1,393,514 + Rv1249c 0.41 -0.3
1,393,587 + Rv1249c 0.50 -0.1
1,393,687 - Rv1249c 0.62 +0.0
1,393,705 - Rv1249c 0.65 +1.0
1,393,705 - Rv1249c 0.65 +1.8
1,393,705 - Rv1249c 0.65 -0.1
1,393,810 + Rv1249c 0.78 +0.0
1,393,810 + Rv1249c 0.78 -0.3
1,393,810 + Rv1249c 0.78 +0.2
1,393,810 + Rv1249c 0.78 +0.2
1,393,810 + Rv1249c 0.78 +0.0
1,393,810 + Rv1249c 0.78 +0.4
1,393,810 + Rv1249c 0.78 -0.5
1,393,810 + Rv1249c 0.78 -0.0
1,393,810 + Rv1249c 0.78 +0.4
1,393,810 + Rv1249c 0.78 -0.1
1,393,811 - Rv1249c 0.78 -0.3
1,393,811 - Rv1249c 0.78 +0.3
1,394,079 + +0.2
1,394,178 + +0.0
1,394,179 - -0.5
1,394,179 - +0.0
1,394,179 - +0.9
1,394,185 - -0.2
1,394,216 - -0.5
1,394,292 - +0.1
1,394,325 - -0.2
1,394,365 + Rv1250 0.11 +0.0
1,394,377 + Rv1250 0.11 -0.3
1,394,551 - Rv1250 0.21 -0.1
1,394,769 - Rv1250 0.34 -0.0
1,394,847 - Rv1250 0.38 -0.9

Or see this region's nucleotide sequence