Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1235

Experiment: D-Trehalose 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1233c and Rv1234 are separated by 149 nucleotidesRv1234 and Rv1235 are separated by 20 nucleotidesRv1235 and Rv1236 overlap by 4 nucleotidesRv1236 and Rv1237 are separated by 4 nucleotides Rv1233c: Rv1233c - Conserved hypothetical membrane protein, at 1,376,230 to 1,376,826 Rv1233c Rv1234: Rv1234 - Probable transmembrane protein, at 1,376,976 to 1,377,503 Rv1234 Rv1235: Rv1235 - Probable sugar-binding lipoprotein LpqY, at 1,377,524 to 1,378,930 Rv1235 Rv1236: Rv1236 - Probable sugar-transport integral membrane protein ABC transporter SugA, at 1,378,927 to 1,379,850 Rv1236 Rv1237: Rv1237 - Probable sugar-transport integral membrane protein ABC transporter SugB, at 1,379,855 to 1,380,679 Rv1237 Position (kb) 1377 1378 1379Strain fitness (log2 ratio) -3 -2 -1 0 1at 1376.539 kb on + strand, within Rv1233cat 1376.539 kb on + strand, within Rv1233cat 1376.539 kb on + strand, within Rv1233cat 1376.539 kb on + strand, within Rv1233cat 1376.539 kb on + strand, within Rv1233cat 1376.540 kb on - strand, within Rv1233cat 1376.540 kb on - strand, within Rv1233cat 1376.540 kb on - strand, within Rv1233cat 1376.540 kb on - strand, within Rv1233cat 1376.540 kb on - strand, within Rv1233cat 1376.595 kb on - strand, within Rv1233cat 1376.645 kb on + strand, within Rv1233cat 1376.897 kb on - strandat 1376.911 kb on - strandat 1376.982 kb on - strandat 1377.130 kb on - strand, within Rv1234at 1377.442 kb on + strand, within Rv1234at 1377.635 kb on + strandat 1377.636 kb on - strandat 1378.198 kb on + strand, within Rv1235at 1378.256 kb on - strand, within Rv1235at 1378.664 kb on + strand, within Rv1235at 1378.665 kb on - strand, within Rv1235at 1378.665 kb on - strand, within Rv1235at 1379.066 kb on - strand, within Rv1236at 1379.079 kb on + strand, within Rv1236at 1379.140 kb on + strand, within Rv1236at 1379.140 kb on + strand, within Rv1236at 1379.140 kb on + strand, within Rv1236at 1379.141 kb on - strand, within Rv1236at 1379.141 kb on - strand, within Rv1236at 1379.165 kb on - strand, within Rv1236at 1379.335 kb on + strand, within Rv1236at 1379.337 kb on + strand, within Rv1236at 1379.338 kb on - strand, within Rv1236at 1379.338 kb on - strand, within Rv1236at 1379.348 kb on - strand, within Rv1236at 1379.348 kb on - strand, within Rv1236at 1379.473 kb on - strand, within Rv1236at 1379.656 kb on + strand, within Rv1236at 1379.657 kb on - strand, within Rv1236at 1379.657 kb on - strand, within Rv1236at 1379.657 kb on - strand, within Rv1236

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Trehalose 10 mM (C)
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1,376,539 + Rv1233c 0.52 -0.4
1,376,539 + Rv1233c 0.52 -0.3
1,376,539 + Rv1233c 0.52 -1.6
1,376,539 + Rv1233c 0.52 -1.2
1,376,539 + Rv1233c 0.52 -0.5
1,376,540 - Rv1233c 0.52 -0.2
1,376,540 - Rv1233c 0.52 -0.4
1,376,540 - Rv1233c 0.52 -0.6
1,376,540 - Rv1233c 0.52 -0.2
1,376,540 - Rv1233c 0.52 -0.4
1,376,595 - Rv1233c 0.61 -0.4
1,376,645 + Rv1233c 0.70 +0.1
1,376,897 - -1.7
1,376,911 - -1.7
1,376,982 - -2.2
1,377,130 - Rv1234 0.29 -1.8
1,377,442 + Rv1234 0.88 -1.5
1,377,635 + -2.7
1,377,636 - -2.3
1,378,198 + Rv1235 0.48 -2.1
1,378,256 - Rv1235 0.52 -1.5
1,378,664 + Rv1235 0.81 -1.8
1,378,665 - Rv1235 0.81 -1.5
1,378,665 - Rv1235 0.81 -2.4
1,379,066 - Rv1236 0.15 -2.3
1,379,079 + Rv1236 0.16 -1.2
1,379,140 + Rv1236 0.23 -3.3
1,379,140 + Rv1236 0.23 -2.0
1,379,140 + Rv1236 0.23 -3.0
1,379,141 - Rv1236 0.23 -1.3
1,379,141 - Rv1236 0.23 -1.5
1,379,165 - Rv1236 0.26 -0.1
1,379,335 + Rv1236 0.44 +0.3
1,379,337 + Rv1236 0.44 -1.2
1,379,338 - Rv1236 0.44 -2.0
1,379,338 - Rv1236 0.44 -2.4
1,379,348 - Rv1236 0.46 -0.2
1,379,348 - Rv1236 0.46 -1.2
1,379,473 - Rv1236 0.59 -2.3
1,379,656 + Rv1236 0.79 -1.8
1,379,657 - Rv1236 0.79 -1.5
1,379,657 - Rv1236 0.79 -1.4
1,379,657 - Rv1236 0.79 -2.1

Or see this region's nucleotide sequence