Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3685c

Experiment: D-Trehalose 10 mM (C)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3684 and GFF3829 are separated by 61 nucleotidesGFF3829 and Rv3685c are separated by 680 nucleotidesRv3685c and Rv3686c are separated by 25 nucleotidesRv3686c and Rv3687c are separated by 239 nucleotides Rv3684: Rv3684 - Probable lyase, at 4,125,439 to 4,126,479 Rv3684 GFF3829 - tRNA-Pro, at 4,126,541 to 4,126,614 GFF3829 Rv3685c: Rv3685c - Probable cytochrome P450 137 Cyp137, at 4,127,295 to 4,128,725 Rv3685c Rv3686c: Rv3686c - Conserved hypothetical protein, at 4,128,751 to 4,129,083 Rv3686c Rv3687c: Rv3687c - Anti-anti-sigma factor RsfB (anti-sigma factor antagonist) (regulator of sigma F B), at 4,129,323 to 4,129,691 Rv3687c Position (kb) 4127 4128 4129Strain fitness (log2 ratio) -1 0 1 2at 4126.372 kb on + strand, within Rv3684at 4126.373 kb on - strand, within Rv3684at 4126.384 kb on + strandat 4126.385 kb on - strandat 4126.385 kb on - strandat 4126.521 kb on + strandat 4126.657 kb on - strandat 4126.657 kb on - strandat 4126.756 kb on + strandat 4126.756 kb on + strandat 4126.757 kb on - strandat 4126.757 kb on - strandat 4126.877 kb on + strandat 4126.877 kb on + strandat 4126.878 kb on - strandat 4127.019 kb on - strandat 4127.142 kb on + strandat 4127.143 kb on - strandat 4127.422 kb on - strandat 4127.554 kb on + strand, within Rv3685cat 4127.554 kb on + strand, within Rv3685cat 4127.554 kb on + strand, within Rv3685cat 4127.554 kb on + strand, within Rv3685cat 4127.555 kb on - strand, within Rv3685cat 4127.555 kb on - strand, within Rv3685cat 4128.046 kb on + strand, within Rv3685cat 4128.218 kb on + strand, within Rv3685cat 4128.219 kb on - strand, within Rv3685cat 4128.219 kb on - strand, within Rv3685cat 4128.219 kb on - strand, within Rv3685cat 4128.219 kb on - strand, within Rv3685cat 4128.260 kb on - strand, within Rv3685cat 4128.282 kb on + strand, within Rv3685cat 4128.283 kb on - strand, within Rv3685cat 4128.283 kb on - strand, within Rv3685cat 4128.355 kb on + strand, within Rv3685cat 4128.356 kb on - strand, within Rv3685cat 4128.553 kb on + strand, within Rv3685cat 4128.661 kb on - strandat 4128.844 kb on - strand, within Rv3686cat 4128.844 kb on - strand, within Rv3686cat 4128.844 kb on - strand, within Rv3686cat 4128.844 kb on - strand, within Rv3686cat 4128.861 kb on + strand, within Rv3686cat 4128.863 kb on + strand, within Rv3686cat 4128.863 kb on + strand, within Rv3686cat 4128.863 kb on + strand, within Rv3686cat 4128.864 kb on - strand, within Rv3686cat 4128.946 kb on + strand, within Rv3686cat 4128.947 kb on - strand, within Rv3686cat 4129.076 kb on + strandat 4129.077 kb on - strandat 4129.126 kb on + strandat 4129.127 kb on - strandat 4129.277 kb on + strandat 4129.278 kb on - strandat 4129.278 kb on - strandat 4129.278 kb on - strandat 4129.316 kb on + strandat 4129.347 kb on + strandat 4129.649 kb on + strand, within Rv3687c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction D-Trehalose 10 mM (C)
remove
4,126,372 + Rv3684 0.90 -0.2
4,126,373 - Rv3684 0.90 +0.9
4,126,384 + -0.1
4,126,385 - +1.0
4,126,385 - -0.0
4,126,521 + +0.2
4,126,657 - -0.3
4,126,657 - +0.8
4,126,756 + -0.6
4,126,756 + -0.5
4,126,757 - +0.8
4,126,757 - -0.9
4,126,877 + -0.0
4,126,877 + -1.4
4,126,878 - +1.9
4,127,019 - +0.1
4,127,142 + -0.4
4,127,143 - -1.7
4,127,422 - -0.5
4,127,554 + Rv3685c 0.18 -1.0
4,127,554 + Rv3685c 0.18 -0.2
4,127,554 + Rv3685c 0.18 +0.9
4,127,554 + Rv3685c 0.18 -0.1
4,127,555 - Rv3685c 0.18 -0.3
4,127,555 - Rv3685c 0.18 -0.1
4,128,046 + Rv3685c 0.52 -1.0
4,128,218 + Rv3685c 0.65 -0.2
4,128,219 - Rv3685c 0.65 -0.5
4,128,219 - Rv3685c 0.65 +2.2
4,128,219 - Rv3685c 0.65 -1.0
4,128,219 - Rv3685c 0.65 -0.8
4,128,260 - Rv3685c 0.67 -1.5
4,128,282 + Rv3685c 0.69 -1.1
4,128,283 - Rv3685c 0.69 -0.8
4,128,283 - Rv3685c 0.69 +0.3
4,128,355 + Rv3685c 0.74 -0.2
4,128,356 - Rv3685c 0.74 -0.9
4,128,553 + Rv3685c 0.88 -0.8
4,128,661 - +0.7
4,128,844 - Rv3686c 0.28 +0.1
4,128,844 - Rv3686c 0.28 -0.1
4,128,844 - Rv3686c 0.28 -0.7
4,128,844 - Rv3686c 0.28 -0.7
4,128,861 + Rv3686c 0.33 +0.3
4,128,863 + Rv3686c 0.34 -0.1
4,128,863 + Rv3686c 0.34 +0.9
4,128,863 + Rv3686c 0.34 +0.1
4,128,864 - Rv3686c 0.34 -1.2
4,128,946 + Rv3686c 0.59 +0.2
4,128,947 - Rv3686c 0.59 -0.9
4,129,076 + -0.4
4,129,077 - -0.2
4,129,126 + -1.5
4,129,127 - -0.4
4,129,277 + +0.0
4,129,278 - -0.4
4,129,278 - +0.0
4,129,278 - +0.6
4,129,316 + +1.9
4,129,347 + +0.2
4,129,649 + Rv3687c 0.88 -0.3

Or see this region's nucleotide sequence