Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3022A

Experiment: D-Trehalose 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3021c and Rv3022c overlap by 13 nucleotidesRv3022c and Rv3022A overlap by 4 nucleotidesRv3022A and Rv3023c are separated by 381 nucleotides Rv3021c: Rv3021c - PPE family protein PPE47, at 3,379,376 to 3,380,452 Rv3021c Rv3022c: Rv3022c - PPE family protein PPE48, at 3,380,440 to 3,380,682 Rv3022c Rv3022A: Rv3022A - PE family protein PE29, at 3,380,679 to 3,380,993 Rv3022A Rv3023c: Rv3023c - Probable transposase, at 3,381,375 to 3,382,622 Rv3023c Position (kb) 3380 3381Strain fitness (log2 ratio) -1 0 1at 3379.893 kb on - strand, within Rv3021cat 3380.704 kb on + strandat 3380.704 kb on + strandat 3380.824 kb on - strand, within Rv3022Aat 3380.832 kb on - strand, within Rv3022Aat 3380.888 kb on + strand, within Rv3022Aat 3381.011 kb on + strandat 3381.128 kb on - strandat 3381.181 kb on - strandat 3381.274 kb on + strandat 3381.275 kb on - strandat 3381.336 kb on - strandat 3381.336 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D-Trehalose 10 mM (C)
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3,379,893 - Rv3021c 0.48 +0.6
3,380,704 + +0.3
3,380,704 + -0.5
3,380,824 - Rv3022A 0.46 -0.1
3,380,832 - Rv3022A 0.49 +0.2
3,380,888 + Rv3022A 0.66 +0.6
3,381,011 + -1.4
3,381,128 - -0.5
3,381,181 - -0.7
3,381,274 + -0.7
3,381,275 - -0.5
3,381,336 - -0.6
3,381,336 - +0.4

Or see this region's nucleotide sequence