Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1882c

Experiment: D,L-Malic Acid 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1880c and Rv1881c are separated by 49 nucleotidesRv1881c and Rv1882c are separated by 40 nucleotidesRv1882c and Rv1883c are separated by 27 nucleotidesRv1883c and Rv1884c are separated by 38 nucleotides Rv1880c: Rv1880c - Probable cytochrome P450 140 Cyp140, at 2,130,541 to 2,131,857 Rv1880c Rv1881c: Rv1881c - Possible conserved lipoprotein LppE, at 2,131,907 to 2,132,329 Rv1881c Rv1882c: Rv1882c - Probable short-chain type dehydrogenase/reductase, at 2,132,370 to 2,133,203 Rv1882c Rv1883c: Rv1883c - Conserved hypothetical protein, at 2,133,231 to 2,133,692 Rv1883c Rv1884c: Rv1884c - Probable resuscitation-promoting factor RpfC, at 2,133,731 to 2,134,261 Rv1884c Position (kb) 2132 2133 2134Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 2131.370 kb on - strand, within Rv1880cat 2131.370 kb on - strand, within Rv1880cat 2131.676 kb on + strand, within Rv1880cat 2131.676 kb on + strand, within Rv1880cat 2131.724 kb on + strand, within Rv1880cat 2131.894 kb on + strandat 2131.894 kb on + strandat 2131.895 kb on - strandat 2131.895 kb on - strandat 2131.995 kb on + strand, within Rv1881cat 2131.995 kb on + strand, within Rv1881cat 2131.995 kb on + strand, within Rv1881cat 2131.995 kb on + strand, within Rv1881cat 2131.995 kb on + strand, within Rv1881cat 2131.996 kb on - strand, within Rv1881cat 2131.996 kb on - strand, within Rv1881cat 2131.996 kb on - strand, within Rv1881cat 2131.996 kb on - strand, within Rv1881cat 2132.117 kb on + strand, within Rv1881cat 2132.117 kb on + strand, within Rv1881cat 2132.118 kb on - strand, within Rv1881cat 2132.118 kb on - strand, within Rv1881cat 2132.371 kb on + strandat 2132.372 kb on - strandat 2132.479 kb on + strand, within Rv1882cat 2132.479 kb on + strand, within Rv1882cat 2132.479 kb on + strand, within Rv1882cat 2132.479 kb on + strand, within Rv1882cat 2132.479 kb on + strand, within Rv1882cat 2132.480 kb on - strand, within Rv1882cat 2132.506 kb on + strand, within Rv1882cat 2132.755 kb on + strand, within Rv1882cat 2132.766 kb on - strand, within Rv1882cat 2132.779 kb on + strand, within Rv1882cat 2132.779 kb on + strand, within Rv1882cat 2132.779 kb on + strand, within Rv1882cat 2132.780 kb on - strand, within Rv1882cat 2132.780 kb on - strand, within Rv1882cat 2132.780 kb on - strand, within Rv1882cat 2132.780 kb on - strand, within Rv1882cat 2132.780 kb on - strand, within Rv1882cat 2132.836 kb on + strand, within Rv1882cat 2132.836 kb on + strand, within Rv1882cat 2132.836 kb on + strand, within Rv1882cat 2132.837 kb on - strand, within Rv1882cat 2132.837 kb on - strand, within Rv1882cat 2132.837 kb on - strand, within Rv1882cat 2132.851 kb on + strand, within Rv1882cat 2133.075 kb on + strand, within Rv1882cat 2133.076 kb on - strand, within Rv1882cat 2133.112 kb on - strand, within Rv1882cat 2133.120 kb on + strandat 2133.120 kb on + strandat 2133.120 kb on + strandat 2133.120 kb on + strandat 2133.121 kb on - strandat 2133.325 kb on + strand, within Rv1883cat 2133.325 kb on + strand, within Rv1883cat 2133.325 kb on + strand, within Rv1883cat 2133.326 kb on - strand, within Rv1883cat 2133.326 kb on - strand, within Rv1883cat 2133.328 kb on + strand, within Rv1883cat 2133.329 kb on - strand, within Rv1883cat 2133.329 kb on - strand, within Rv1883cat 2133.406 kb on + strand, within Rv1883cat 2133.474 kb on + strand, within Rv1883cat 2133.474 kb on + strand, within Rv1883cat 2133.692 kb on + strandat 2133.692 kb on + strandat 2133.693 kb on - strandat 2133.693 kb on - strandat 2133.708 kb on + strandat 2134.193 kb on + strand, within Rv1884c

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Per-strain Table

Position Strand Gene LocusTag Fraction D,L-Malic Acid 10 mM (C)
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2,131,370 - Rv1880c 0.63 +2.0
2,131,370 - Rv1880c 0.63 -0.5
2,131,676 + Rv1880c 0.86 -0.1
2,131,676 + Rv1880c 0.86 -0.1
2,131,724 + Rv1880c 0.90 -0.1
2,131,894 + -0.0
2,131,894 + -0.7
2,131,895 - +0.5
2,131,895 - +0.5
2,131,995 + Rv1881c 0.21 -0.5
2,131,995 + Rv1881c 0.21 +0.7
2,131,995 + Rv1881c 0.21 -1.6
2,131,995 + Rv1881c 0.21 -0.2
2,131,995 + Rv1881c 0.21 -1.0
2,131,996 - Rv1881c 0.21 -0.2
2,131,996 - Rv1881c 0.21 +2.6
2,131,996 - Rv1881c 0.21 -0.3
2,131,996 - Rv1881c 0.21 -0.0
2,132,117 + Rv1881c 0.50 +1.0
2,132,117 + Rv1881c 0.50 +1.1
2,132,118 - Rv1881c 0.50 +1.3
2,132,118 - Rv1881c 0.50 +0.1
2,132,371 + -0.3
2,132,372 - -0.1
2,132,479 + Rv1882c 0.13 -2.5
2,132,479 + Rv1882c 0.13 -2.7
2,132,479 + Rv1882c 0.13 -0.1
2,132,479 + Rv1882c 0.13 -1.1
2,132,479 + Rv1882c 0.13 -0.9
2,132,480 - Rv1882c 0.13 +0.0
2,132,506 + Rv1882c 0.16 +0.1
2,132,755 + Rv1882c 0.46 +0.8
2,132,766 - Rv1882c 0.47 -0.3
2,132,779 + Rv1882c 0.49 -1.1
2,132,779 + Rv1882c 0.49 -0.0
2,132,779 + Rv1882c 0.49 -1.0
2,132,780 - Rv1882c 0.49 +0.2
2,132,780 - Rv1882c 0.49 +0.0
2,132,780 - Rv1882c 0.49 -0.2
2,132,780 - Rv1882c 0.49 +0.3
2,132,780 - Rv1882c 0.49 +0.1
2,132,836 + Rv1882c 0.56 -0.6
2,132,836 + Rv1882c 0.56 -0.8
2,132,836 + Rv1882c 0.56 -0.5
2,132,837 - Rv1882c 0.56 +1.6
2,132,837 - Rv1882c 0.56 -0.2
2,132,837 - Rv1882c 0.56 -0.5
2,132,851 + Rv1882c 0.58 +0.4
2,133,075 + Rv1882c 0.85 -0.6
2,133,076 - Rv1882c 0.85 +0.8
2,133,112 - Rv1882c 0.89 -0.3
2,133,120 + +0.1
2,133,120 + +0.8
2,133,120 + +0.2
2,133,120 + -0.0
2,133,121 - -1.4
2,133,325 + Rv1883c 0.20 -0.3
2,133,325 + Rv1883c 0.20 +0.4
2,133,325 + Rv1883c 0.20 -0.2
2,133,326 - Rv1883c 0.21 -1.2
2,133,326 - Rv1883c 0.21 +0.2
2,133,328 + Rv1883c 0.21 -0.2
2,133,329 - Rv1883c 0.21 -0.9
2,133,329 - Rv1883c 0.21 -2.8
2,133,406 + Rv1883c 0.38 -0.5
2,133,474 + Rv1883c 0.53 +0.5
2,133,474 + Rv1883c 0.53 -0.0
2,133,692 + +0.4
2,133,692 + -0.0
2,133,693 - -0.2
2,133,693 - -0.2
2,133,708 + -0.4
2,134,193 + Rv1884c 0.87 -0.8

Or see this region's nucleotide sequence