Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1537

Experiment: D,L-Malic Acid 10 mM (C)

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1536 and Rv1537 are separated by 211 nucleotidesRv1537 and Rv1538c overlap by 36 nucleotidesRv1538c and Rv1539 are separated by 51 nucleotides Rv1536: Rv1536 - Isoleucyl-tRNA synthetase IleS, at 1,736,519 to 1,739,644 Rv1536 Rv1537: Rv1537 - Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)), at 1,739,856 to 1,741,247 Rv1537 Rv1538c: Rv1538c - Probable L-aparaginase AnsA, at 1,741,212 to 1,742,192 Rv1538c Rv1539: Rv1539 - Probable lipoprotein signal peptidase LspA, at 1,742,244 to 1,742,852 Rv1539 Position (kb) 1739 1740 1741 1742Strain fitness (log2 ratio) -3 -2 -1 0 1at 1739.811 kb on - strandat 1739.811 kb on - strandat 1739.828 kb on + strandat 1739.829 kb on - strandat 1739.829 kb on - strandat 1739.980 kb on - strandat 1739.995 kb on - strandat 1740.494 kb on - strand, within Rv1537at 1740.716 kb on - strand, within Rv1537at 1740.739 kb on + strand, within Rv1537at 1740.936 kb on + strand, within Rv1537at 1741.174 kb on - strandat 1741.270 kb on - strandat 1741.348 kb on + strand, within Rv1538cat 1741.610 kb on - strand, within Rv1538cat 1741.867 kb on + strand, within Rv1538cat 1741.868 kb on - strand, within Rv1538cat 1741.868 kb on - strand, within Rv1538cat 1741.904 kb on + strand, within Rv1538cat 1741.972 kb on - strand, within Rv1538cat 1742.028 kb on + strand, within Rv1538cat 1742.029 kb on - strand, within Rv1538cat 1742.029 kb on - strand, within Rv1538cat 1742.091 kb on + strand, within Rv1538cat 1742.136 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction D,L-Malic Acid 10 mM (C)
remove
1,739,811 - -0.1
1,739,811 - -0.5
1,739,828 + +1.2
1,739,829 - -2.6
1,739,829 - +0.2
1,739,980 - -1.1
1,739,995 - +0.3
1,740,494 - Rv1537 0.46 +0.1
1,740,716 - Rv1537 0.62 +0.4
1,740,739 + Rv1537 0.63 -1.3
1,740,936 + Rv1537 0.78 -0.3
1,741,174 - -0.8
1,741,270 - +0.6
1,741,348 + Rv1538c 0.14 -2.2
1,741,610 - Rv1538c 0.41 -1.5
1,741,867 + Rv1538c 0.67 +1.4
1,741,868 - Rv1538c 0.67 -1.7
1,741,868 - Rv1538c 0.67 -1.8
1,741,904 + Rv1538c 0.71 -0.4
1,741,972 - Rv1538c 0.77 -2.0
1,742,028 + Rv1538c 0.83 -1.0
1,742,029 - Rv1538c 0.83 -1.8
1,742,029 - Rv1538c 0.83 +1.6
1,742,091 + Rv1538c 0.90 -2.8
1,742,136 - -3.0

Or see this region's nucleotide sequence