Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3257c

Experiment: D,L-Malic Acid 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3256c and Rv3257c overlap by 4 nucleotidesRv3257c and Rv3258c are separated by 101 nucleotidesRv3258c and Rv3259 are separated by 122 nucleotides Rv3256c: Rv3256c - Conserved protein, at 3,636,275 to 3,637,315 Rv3256c Rv3257c: Rv3257c - Probable phosphomannomutase PmmA (PMM) (phosphomannose mutase), at 3,637,312 to 3,638,709 Rv3257c Rv3258c: Rv3258c - Conserved hypothetical protein, at 3,638,811 to 3,639,302 Rv3258c Rv3259: Rv3259 - Conserved hypothetical protein, at 3,639,425 to 3,639,844 Rv3259 Position (kb) 3637 3638 3639Strain fitness (log2 ratio) -1 0 1at 3636.826 kb on - strand, within Rv3256cat 3637.083 kb on - strand, within Rv3256cat 3638.759 kb on + strandat 3638.813 kb on - strandat 3639.506 kb on + strand, within Rv3259at 3639.506 kb on + strand, within Rv3259at 3639.506 kb on + strand, within Rv3259at 3639.507 kb on - strand, within Rv3259

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Per-strain Table

Position Strand Gene LocusTag Fraction D,L-Malic Acid 10 mM (C)
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3,636,826 - Rv3256c 0.53 +1.2
3,637,083 - Rv3256c 0.78 +0.5
3,638,759 + -0.6
3,638,813 - +0.2
3,639,506 + Rv3259 0.19 +1.3
3,639,506 + Rv3259 0.19 +1.1
3,639,506 + Rv3259 0.19 -0.3
3,639,507 - Rv3259 0.20 +0.2

Or see this region's nucleotide sequence