Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2625c

Experiment: D,L-Malic Acid 10 mM (C)

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2623 and Rv2624c are separated by 2 nucleotidesRv2624c and Rv2625c are separated by 14 nucleotidesRv2625c and Rv2626c are separated by 58 nucleotides Rv2623: Rv2623 - Universal stress protein family protein TB31.7, at 2,949,593 to 2,950,486 Rv2623 Rv2624c: Rv2624c - Universal stress protein family protein, at 2,950,489 to 2,951,307 Rv2624c Rv2625c: Rv2625c - Probable conserved transmembrane alanine and leucine rich protein, at 2,951,322 to 2,952,503 Rv2625c Rv2626c: Rv2626c - Hypoxic response protein 1 Hrp1, at 2,952,562 to 2,952,993 Rv2626c Position (kb) 2951 2952 2953Strain fitness (log2 ratio) -1 0 1at 2950.485 kb on - strandat 2950.661 kb on + strand, within Rv2624cat 2951.141 kb on + strand, within Rv2624cat 2951.263 kb on - strandat 2951.579 kb on + strand, within Rv2625cat 2951.693 kb on - strand, within Rv2625cat 2951.963 kb on + strand, within Rv2625cat 2951.986 kb on + strand, within Rv2625cat 2952.759 kb on - strand, within Rv2626cat 2952.914 kb on + strand, within Rv2626cat 2952.914 kb on + strand, within Rv2626cat 2953.020 kb on - strandat 2953.066 kb on - strandat 2953.106 kb on - strandat 2953.201 kb on + strandat 2953.201 kb on + strandat 2953.373 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction D,L-Malic Acid 10 mM (C)
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2,950,485 - -0.0
2,950,661 + Rv2624c 0.21 +1.7
2,951,141 + Rv2624c 0.80 +0.4
2,951,263 - +1.1
2,951,579 + Rv2625c 0.22 +0.3
2,951,693 - Rv2625c 0.31 -0.1
2,951,963 + Rv2625c 0.54 -0.4
2,951,986 + Rv2625c 0.56 +0.8
2,952,759 - Rv2626c 0.46 -0.2
2,952,914 + Rv2626c 0.81 +0.8
2,952,914 + Rv2626c 0.81 -0.1
2,953,020 - -0.4
2,953,066 - +0.7
2,953,106 - -0.0
2,953,201 + -0.3
2,953,201 + +0.2
2,953,373 + +0.6

Or see this region's nucleotide sequence